Literature DB >> 25653129

Novel reassortant highly pathogenic H5N6 avian influenza viruses in poultry in China.

Haibo Wu1, Rufeng Lu2, Xiaorong Peng1, Lihua Xu3, Linfang Cheng1, Xiangyun Lu1, Changzhong Jin1, Tiansheng Xie1, Hangping Yao1, Nanping Wu4.   

Abstract

We characterized two novel highly pathogenic H5N6 influenza viruses isolated from Chinese poultry in 2013. Genomic analysis showed that both isolates were reassortants, and derived their genes from H5 and H6 subtype viruses found in poultry in China. The virulence of the two isolates was examined in chickens and mice, and both isolates were found to be highly pathogenic in chickens and only moderately virulent for mice. Our results show that continued circulation of these viruses could endanger both avian species and humans.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Avian influenza virus; China; H5N6; Poultry; Virus reassortment

Mesh：

Year:  2015        PMID： 25653129     DOI： 10.1016/j.meegid.2015.01.019

Source DB:  PubMed          Journal:  Infect Genet Evol        ISSN： 1567-1348            Impact factor:   3.342


  24 in total

1.  Molecular Evolution and Emergence of H5N6 Avian Influenza Virus in Central China.

Authors:  Yingying Du; Mingyue Chen; Jiayun Yang; Yane Jia; Shufang Han; Edward C Holmes; Jie Cui
Journal:  J Virol       Date:  2017-05-26       Impact factor: 5.103

2.  A single dose of a vesicular stomatitis virus-based influenza vaccine confers rapid protection against H5 viruses from different clades.

Authors:  Wakako Furuyama; Pierce Reynolds; Elaine Haddock; Kimberly Meade-White; Mai Quynh Le; Yoshihiro Kawaoka; Heinz Feldmann; Andrea Marzi
Journal:  NPJ Vaccines       Date:  2020-01-10       Impact factor: 7.344

3.  Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain.

Authors:  Xuxiao Zhang; Juan Pu; Yipeng Sun; Bi Yuhai; Zhimin Jiang; Guanlong Xu; Hongyu Zhang; Jing Cao; Kin-Chow Chang; Jinhua Liu; Honglei Sun
Journal:  J Virol       Date:  2021-01-06       Impact factor: 5.103

4.  Isolation and characterization of two novel reassortant H5N6 avian influenza viruses from waterfowl in eastern China.

Authors:  Fan Yang; Yixin Xiao; Fumin Liu; Hangping Yao; Nanping Wu; Haibo Wu
Journal:  Arch Virol       Date:  2021-02-17       Impact factor: 2.574

5.  Artificial infectious disease optimization: A SEIQR epidemic dynamic model-based function optimization algorithm.

Authors:  Guangqiu Huang
Journal:  Swarm Evol Comput       Date:  2015-10-09       Impact factor: 7.177

6.  H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?

Authors:  Gabriele Neumann
Journal:  Future Virol       Date:  2015       Impact factor: 1.831

7.  Clinical, epidemiological and virological characteristics of the first detected human case of avian influenza A(H5N6) virus.

Authors:  Rusheng Zhang; Tianmu Chen; Xinhua Ou; Ruchun Liu; Yang Yang; Wen Ye; Jingfang Chen; Dong Yao; Biancheng Sun; Xixing Zhang; Jianxiang Zhou; Yan Sun; Faming Chen; Shi-Ping Wang
Journal:  Infect Genet Evol       Date:  2016-03-10       Impact factor: 3.342

8.  Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model Ferrets.

Authors:  Honglei Sun; Juan Pu; Yandi Wei; Yipeng Sun; Jiao Hu; Litao Liu; Guanlong Xu; Weihua Gao; Chong Li; Xuxiao Zhang; Yinhua Huang; Kin-Chow Chang; Xiufan Liu; Jinhua Liu
Journal:  J Virol       Date:  2016-06-24       Impact factor: 5.103

9.  Co-circulation of H5N6, H3N2, H3N8, and Emergence of Novel Reassortant H3N6 in a Local Community in Hunan Province in China.

Authors:  Xuyong Li; Jiayun Yang; Bin Liu; Yane Jia; Jing Guo; Xue Gao; Shaoting Weng; Maijuan Yang; Liang Wang; Lin-Fa Wang; Jie Cui; Hualan Chen; Qiyun Zhu
Journal:  Sci Rep       Date:  2016-05-06       Impact factor: 4.379

10.  Continuing Reassortant of H5N6 Subtype Highly Pathogenic Avian Influenza Virus in Guangdong.

Authors:  Runyu Yuan; Zheng Wang; Yinfeng Kang; Jie Wu; Lirong Zou; Lijun Liang; Yingchao Song; Xin Zhang; Hanzhong Ni; Jinyan Lin; Changwen Ke
Journal:  Front Microbiol       Date:  2016-04-13       Impact factor: 5.640
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