| Literature DB >> 2565252 |
A Horsch1, C Martins de Sa, B Dineva, E Spindler, H P Schmid.
Abstract
Prosomes are small cytoplasmic RNP complexes associated with repressed mRNA. In in vitro translation, they discriminate between the mRNA of adenovirus-infected HeLa cells and those of uninfected cells grown under normal conditions. Prosomes as well as their RNA constituents interact much more strongly with poly(A)+ mRNA of infected cells and inhibit their translation in vitro preferentially. A possible role of prosomes in the differential regulation of translation is discussed.Entities:
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Year: 1989 PMID: 2565252 DOI: 10.1016/0014-5793(89)80268-6
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124