Sir,The report on “neurocysticercosis and afebrile seizure[3]” is very interesting. SAHU et al. noted that “neurocysticercosis
should be suspected in every child presenting with afebrile seizure especially with a
radio-imaging supportive diagnosis in tropical developing countries or areas endemic for teniasis/cysticercosis[3]”. In fact, neurocysticercosis is a very important tropical neurological infection.
This disease can be seen worldwide. The MRI finding and immune response in
neurocysticercosis is very interesting. KISHORE et al. found that “immune
response was sub-optimal even in MRI positive cases and conversely, few MRI negative cases
were seropositive[1].” Hence, to diagnose, both investigations are necessary[1]. Furthermore, there are many concerns on treatment of the neurocysticercosis
presenting with afebrile seizure. First, the efficacy of antiparasitic drug might be
reduced due to drug interaction with antiepileptic drug[2]. To manage the case of neurocysticercosis, searching for possible infestation in
other organs of the patient is suggested since disseminated infestation can be expected.
Also, other concomitant parasitic infestation must be searched for.