Literature DB >> 25651224

Management of acute spinal cord injury.

Deborah M Stein, Kevin N Sheth.   

Abstract

PURPOSE OF REVIEW: This article provides an overview of acute spinal cord injury with an emphasis on practical issues regarding initial evaluation and management. Spinal cord injury continues to be a devastating neurologic injury and a significant public health burden, both in terms of patient morbidity as well as societal costs. Optimal management is highly dependent on a strong multidisciplinary and interprofessional collaborative approach. RECENT
FINDINGS: In contrast to prior experience, current guidelines strongly suggest avoidance of steroids in patients with spinal cord injury. Additionally, early evaluation with MRI and decompressive surgery can be important for achieving good outcomes.
SUMMARY: Effective management of acute spinal cord injury requires a team skilled in the approach to short- and long-term respiratory management as well as vigilance for common secondary complications including systemic thrombosis, infection, and pain syndromes.

Entities:  

Mesh:

Year:  2015        PMID: 25651224     DOI: 10.1212/01.CON.0000461091.09736.0c

Source DB:  PubMed          Journal:  Continuum (Minneap Minn)        ISSN: 1080-2371


  9 in total

1.  Protective effect of Oxymatrine against acute spinal cord injury in rats via modulating oxidative stress, inflammation and apoptosis.

Authors:  Binggang Guan; Rongchun Chen; Mingliang Zhong; Ning Liu; Qin Chen
Journal:  Metab Brain Dis       Date:  2019-12-15       Impact factor: 3.584

Review 2.  Pharmacologic and Acute Management of Spinal Cord Injury in Adults and Children.

Authors:  Ajay X Thomas; James J Riviello; Daniel Davila-Williams; Sruthi P Thomas; Jennifer C Erklauer; David F Bauer; Jon A Cokley
Journal:  Curr Treat Options Neurol       Date:  2022-06-10       Impact factor: 3.972

3.  Ultrashortwave radiation promotes the recovery of spinal cord injury by inhibiting inflammation via suppression of the MK2/TNF‑α pathway.

Authors:  Nan Wang; Zhiping Feng; Wei Zhao; Zhiqiang Zhang; Lixin Zhang
Journal:  Int J Mol Med       Date:  2018-07-19       Impact factor: 4.101

4.  The Prognostic Value of Serum Neuron Specific Enolase (NSE) and S100B Level in Patients of Acute Spinal Cord Injury.

Authors:  Wenjun Du; Huinan Li; Juan Sun; Yingpeng Xia; Rusen Zhu; Xueli Zhang; Rong Tian
Journal:  Med Sci Monit       Date:  2018-06-30

Review 5.  Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar.

Authors:  Qi-Ming Pang; Si-Yu Chen; Qi-Jing Xu; Sheng-Ping Fu; Yi-Chun Yang; Wang-Hui Zou; Meng Zhang; Juan Liu; Wei-Hong Wan; Jia-Chen Peng; Tao Zhang
Journal:  Front Immunol       Date:  2021-12-02       Impact factor: 7.561

Review 6.  Can a Scaffold Enriched with Mesenchymal Stem Cells Be a Good Treatment for Spinal Cord Injury?

Authors:  Santino Blando; Ivan Anchesi; Emanuela Mazzon; Agnese Gugliandolo
Journal:  Int J Mol Sci       Date:  2022-07-07       Impact factor: 6.208

7.  Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy.

Authors:  Eric J Marrotte; Khari Johnson; Ryan M Schweller; Rachel Chapla; Brian E Mace; Daniel T Laskowitz; Jennifer L West
Journal:  Crit Care Explor       Date:  2021-06-14

Review 8.  Guideline for diagnosis and treatment of spine trauma in the epidemic of COVID-19.

Authors:  Yu-Long Wang; Feng-Zhao Zhu; Lian Zeng; Dionne Telemacque; Jamal Ahmad Saleem Alshorman; Jin-Ge Zhou; Ze-Kang Xiong; Ting-Fang Sun; Yan-Zhen Qu; Sheng Yao; Tian-Sheng Sun; Shi-Qing Feng; Xiao-Dong Guo
Journal:  Chin J Traumatol       Date:  2020-06-17

Review 9.  Clinical Neurorestorative Therapeutic Guidelines for Spinal Cord Injury (IANR/CANR version 2019).

Authors:  Hongyun Huang; Wise Young; Stephen Skaper; Lin Chen; Gustavo Moviglia; Hooshang Saberi; Ziad Al-Zoubi; Hari Shanker Sharma; Dafin Muresanu; Alok Sharma; Wagih El Masry; Shiqing Feng
Journal:  J Orthop Translat       Date:  2019-11-11       Impact factor: 5.191

  9 in total

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