Luis F Del Castillo1, Ana R Ferreira da Silva2, Saul I Hernández3, M Aguilella4, Andreu Andrio4, Sergio Mollá5, Vicente Compañ6. 1. Departamento de Polímeros, Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Apartado Postal 70-360, Coyoacán, México, DF 04510, Mexico. 2. Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), School of Sciences, University of Minho, Braga, Portugal. 3. Departamento de Física, Universidad Autónoma Metropolitana-Iztapalapa, Apdo. Postal 55-534, 09340 México, DF, Mexico. 4. Departamento de Física Aplicada, Universitat Jaume I, 12080 Castellón, Spain. 5. Departamento de Termodinámica Aplicada, Escuela Técnica Superior de Ingenieros Industriales (ETSII), Universidad Politécnica de Valencia, Campus de Vera s/n, 46020 Valencia, Spain. 6. Departamento de Termodinámica Aplicada, Escuela Técnica Superior de Ingenieros Industriales (ETSII), Universidad Politécnica de Valencia, Campus de Vera s/n, 46020 Valencia, Spain. Electronic address: vicommo@ter.upv.es.
Abstract
PURPOSE: We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (P(O2) ) obtained from in vivo estimation previously reported by other authors. (1) METHODS: Assuming that the cornea is a single homogeneous layer, the oxygen permeability through the cornea will be the same regardless of the type of lens that is available on it. The obtention of the real value of the maximum oxygen consumption rate Qc,max is very important because this parameter is directly related with the gradient pressure profile into the cornea and moreover, the real corneal oxygen consumption is influenced by both anterior and posterior oxygen fluxes. RESULTS: Our calculations give different values for the maximum oxygen consumption rate Qc,max, when different oxygen pressure values (high and low P(O2)) are considered at the interface cornea-tears film. CONCLUSION: Present results are relevant for the calculation on the partial pressure of oxygen, available at different depths into the corneal tissue behind contact lenses of different oxygen transmissibility.
PURPOSE: We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (P(O2) ) obtained from in vivo estimation previously reported by other authors. (1) METHODS: Assuming that the cornea is a single homogeneous layer, the oxygen permeability through the cornea will be the same regardless of the type of lens that is available on it. The obtention of the real value of the maximum oxygen consumption rate Qc,max is very important because this parameter is directly related with the gradient pressure profile into the cornea and moreover, the real corneal oxygen consumption is influenced by both anterior and posterior oxygen fluxes. RESULTS: Our calculations give different values for the maximum oxygen consumption rate Qc,max, when different oxygen pressure values (high and low P(O2)) are considered at the interface cornea-tears film. CONCLUSION: Present results are relevant for the calculation on the partial pressure of oxygen, available at different depths into the corneal tissue behind contact lenses of different oxygen transmissibility.
Keywords:
Consumo de oxígeno de la córnea; Corneal oxygen consumption; Corneal oxygen permeability; Corneal oxygen pressure; Monod kinetics model; modelo cinético de Monod; permeabilidad al oxígeno de la córnea; presión del oxígeno en la córnea
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