Literature DB >> 25649486

Cytokine profiles in Mycoplasma pneumoniae infection-associated hemophagocytic lymphohistiocytosis.

Motoko Yasutomi1, Shintaro Okazaki2, Ikue Hata2, Akihiko Tanizawa2, Soichi Tamamura3, Mikiko Kawakita4, Yusei Ohshima2.   

Abstract

A 3-year-old boy with Mycoplasma pneumoniae infection associated with hemophagocytic lymphohistiocytosis (MP-HLH) presented with an elevated level of serum interleukin-12 (IL-12) and lower levels of interferon-γ and IL-10 compared to patients with Epstein-Barr virus infection associated with HLH (EBV-HLH). Unlike the patients with EBV-HLH, CD8+ CD5low HLA-DR++ T cells were not detected in our pediatric patient. Thus, the pathophysiology of MP-HLH may differ from that of EBV-HLH.
Copyright © 2015. Published by Elsevier B.V.

Entities:  

Keywords:  CD8; Mycoplasma pneumoniae; cytokine; hemophagocytic lymphohistiocytosis

Mesh：

Substances：

Year:  2014        PMID： 25649486     DOI： 10.1016/j.jmii.2014.11.015

Source DB:  PubMed          Journal:  J Microbiol Immunol Infect        ISSN： 1684-1182            Impact factor:   4.399


  5 in total

Review 1.  Mycoplasma pneumoniae from the Respiratory Tract and Beyond.

Authors:  Ken B Waites; Li Xiao; Yang Liu; Mitchell F Balish; T Prescott Atkinson
Journal:  Clin Microbiol Rev       Date:  2017-07       Impact factor: 26.132

2.  A xenograft model of macrophage activation syndrome amenable to anti-CD33 and anti-IL-6R treatment.

Authors:  Mark Wunderlich; Courtney Stockman; Mahima Devarajan; Navin Ravishankar; Christina Sexton; Ashish R Kumar; Benjamin Mizukawa; James C Mulloy
Journal:  JCI Insight       Date:  2016-09-22

3.  Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis.

Authors:  Rupali Das; Peng Guan; Leslee Sprague; Katherine Verbist; Paige Tedrick; Qi Angel An; Cheng Cheng; Makoto Kurachi; Ross Levine; E John Wherry; Scott W Canna; Edward M Behrens; Kim E Nichols
Journal:  Blood       Date:  2016-01-29       Impact factor: 22.113

4.  Mycoplasma infection may complicate the clinical course of SARS-Co-V-2 associated Kawasaki-like disease in children.

Authors:  Alessandro Plebani; Antonella Meini; Marco Cattalini; Vassilios Lougaris; Antonella Bugatti; Francesca Caccuri; Arnaldo Caruso
Journal:  Clin Immunol       Date:  2020-10-16       Impact factor: 3.969

5.  Tuberculosis-Associated HLH in an 8-Month-Old Infant: A Case Report and Review.

Authors:  Holger Hauch; Susanne Skrzypek; Wilhelm Woessmann; Kai Lehmberg; Stephan Ehl; Carsten Speckmann; Emmanuel Schneck; Dieter Koerholz; Christian Jux; Christoph Neuhäuser
Journal:  Front Pediatr       Date:  2020-10-30       Impact factor: 3.418
  5 in total

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