Literature DB >> 25648910

Onco-nephrology: an appraisal of the cancer and chronic kidney disease links.

Hassan Izzedine1, Mark A Perazella2.   

Abstract

A bidirectional relationship has been observed for kidney disease and cancer. On the one hand, cancer is an important complication noted in kidney disease as well as a major cause of morbidity and mortality in this group. On the other hand, improved cancer treatment has prolonged survival, but also increased the development of acute and chronic kidney disease. The combination of cancer and kidney disease makes it challenging for clinicians to provide comprehensive and safe therapies for this group of patients. As such, clinicians caring for this group must develop expertise and become competent in the practice of a newly evolving subspecialty of nephrology known as 'onco-nephrology'. This brief narrative review will focus on the cancer risk in patients with underlying kidney disease, the therapies such as erythropoiesis-stimulating agents on cancer progression and other outcomes, and the appropriate dosing of anti-cancer agents in patients with underlying kidney disease.
© The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Entities:  

Keywords:  albuminuria; cancer; dosage adjustment; erythropoiesis-stimulating agents; kidney disease

Mesh:

Substances:

Year:  2015        PMID: 25648910      PMCID: PMC4832985          DOI: 10.1093/ndt/gfu387

Source DB:  PubMed          Journal:  Nephrol Dial Transplant        ISSN: 0931-0509            Impact factor:   5.992


  105 in total

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4.  Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans.

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Journal:  Cancer       Date:  2001-06-15       Impact factor: 6.860

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8.  September 2007 update on EORTC guidelines and anemia management with erythropoiesis-stimulating agents.

Authors:  Matti S Aapro; Hartmut Link
Journal:  Oncologist       Date:  2008

9.  Cancer risk following organ transplantation: a nationwide cohort study in Sweden.

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