Ana Castaño Carou1, Salvador Pita Fernández2, Sonia Pértega Díaz3, Francisco Javier de Toro Santos4. 1. Centro de Salud de Pontevea, Xerencia de Xestión Integrada de Santiago de Compostela, Santiago de Compostela, A Coruña, España. 2. Grupo de Investigación de Epidemiología Clínica y Bioestadística, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade de A Coruña, A Coruña, España. Electronic address: salvador.pita.fernandez@sergas.es. 3. Grupo de Investigación de Epidemiología Clínica y Bioestadística, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade de A Coruña, A Coruña, España. 4. Servicio de Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade de A Coruña, A Coruña, España.
Abstract
OBJECTIVE: To determine the clinical profile, degree of involvement and management in patients with knee, hip or hand osteoarthritis. MATERIAL AND METHOD: Observational study (health centers from 14 autonomous regions, n=363 primary care physicians), involving patients with clinical and/or radiological criteria for osteoarthritis from the American College of Rheumatology, consecutively selected (n=1,258). Sociodemographic variables, clinical and radiological findings, comorbidity and therapeutic management were analyzed. RESULTS: Mean age was 68.0±9.5 years old; 77.8% were women and 47.6% obese. Distribution by location was: 84.3% knee, 23.4% hip, 14.7% hands. All patients reported pain. The most frequent radiographic Kellgren-Lawrence grade was stage 3 for knee and hip (42.9% and 51.9%, respectively), and 3 (37.2%) and 2 (34.5%) for hip. Time since onset of osteoarthritis symptoms was 9.4±7.5 years, with a mean age at onset of around 60 years old and a family history of osteoarthritis in 66.0%. The most frequent comorbidities were: hypertension (55.1%), depression/anxiety (24.7%) and gastroduodenal diseases (22.9%). A total of 97.6% of the patients received pharmacological treatment, with oral analgesics (paracetamol) (70.5%) and oral NSAIDs (67.9%) being the most frequent drugs. Bilateral osteoarthritis was present in 76.9% of patients with knee osteoarthritis, 59.3% in hip and 94.7% in hands. Female gender and time since onset were associated with bilateral knee and hip osteoarthritis. CONCLUSIONS: The profile of the osteoarthritis patient is female, >65 years old, overweight/obese, with comorbidity, frequent symptoms and moderate radiologic involvement. Most of patients had bilateral osteoarthritis, associated with female gender and time since onset of disease. Paracetamol was the most common pharmacological treatment.
OBJECTIVE: To determine the clinical profile, degree of involvement and management in patients with knee, hip or hand osteoarthritis. MATERIAL AND METHOD: Observational study (health centers from 14 autonomous regions, n=363 primary care physicians), involving patients with clinical and/or radiological criteria for osteoarthritis from the American College of Rheumatology, consecutively selected (n=1,258). Sociodemographic variables, clinical and radiological findings, comorbidity and therapeutic management were analyzed. RESULTS: Mean age was 68.0±9.5 years old; 77.8% were women and 47.6% obese. Distribution by location was: 84.3% knee, 23.4% hip, 14.7% hands. All patients reported pain. The most frequent radiographic Kellgren-Lawrence grade was stage 3 for knee and hip (42.9% and 51.9%, respectively), and 3 (37.2%) and 2 (34.5%) for hip. Time since onset of osteoarthritis symptoms was 9.4±7.5 years, with a mean age at onset of around 60 years old and a family history of osteoarthritis in 66.0%. The most frequent comorbidities were: hypertension (55.1%), depression/anxiety (24.7%) and gastroduodenal diseases (22.9%). A total of 97.6% of the patients received pharmacological treatment, with oral analgesics (paracetamol) (70.5%) and oral NSAIDs (67.9%) being the most frequent drugs. Bilateral osteoarthritis was present in 76.9% of patients with knee osteoarthritis, 59.3% in hip and 94.7% in hands. Female gender and time since onset were associated with bilateral knee and hip osteoarthritis. CONCLUSIONS: The profile of the osteoarthritispatient is female, >65 years old, overweight/obese, with comorbidity, frequent symptoms and moderate radiologic involvement. Most of patients had bilateral osteoarthritis, associated with female gender and time since onset of disease. Paracetamol was the most common pharmacological treatment.
Keywords:
Disease management; Evaluación de los síntomas; Manejo de la enfermedad; Osteoarthritis; Osteoartritis; Signos y síntomas; Signs and symptoms; Symptom assessment
Authors: Martin Brom; Ignacio J Gandino; Johana B Zacariaz Hereter; Marina Scolnik; Florencia B Mollerach; Leandro G Ferreyra Garrott; Josefina Marin; Santiago O Ruta; Javier E Rosa; Ricardo D García-Mónaco; Enrique R Soriano Journal: Front Med (Lausanne) Date: 2020-07-03
Authors: Lilisbeth Perestelo-Pérez; Yolanda Álvarez-Pérez; Amado Rivero-Santana; Vanesa Ramos-García; Andrea Duarte-Díaz; Alezandra Torres-Castaño; Ana Toledo-Chávarri; Mario Herrera-Perez; José Luis País-Brito; José Carlos Del Castillo; José Ramón Vázquez; Carola Orrego; Pedro Serrano-Aguilar Journal: Trials Date: 2020-08-24 Impact factor: 2.279