Literature DB >> 25648458

Review: Beta-thalassemia and molecular chaperones.

Afshan Sumera1, Ammu Radhakrishnan2, Abdul Aziz Baba2, Elizabeth George3.   

Abstract

Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AHSP; HSP-70; Molecular chaperones; Thalassemia

Mesh：

Substances：

Year:  2015        PMID： 25648458     DOI： 10.1016/j.bcmd.2015.01.008

Source DB:  PubMed          Journal:  Blood Cells Mol Dis        ISSN： 1079-9796            Impact factor:   3.039


  4 in total

Review 1.  HbE/β-Thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms and Novel Therapeutics.

Authors:  Rhoda Elison Hirsch; Nathawut Sibmooh; Suthat Fucharoen; Joel M Friedman
Journal:  Antioxid Redox Signal       Date:  2016-11-28       Impact factor: 8.401

Review 2.  What can we learn from ineffective erythropoiesis in thalassemia?

Authors:  Paraskevi Rea Oikonomidou; Stefano Rivella
Journal:  Blood Rev       Date:  2017-10-03       Impact factor: 8.250

Review 3.  The Autophagy-Lysosomal Pathways and Their Emerging Roles in Modulating Proteostasis in Tumors.

Authors:  Zhen Dong; Hongjuan Cui
Journal:  Cells       Date:  2018-12-20       Impact factor: 6.600

4.  Economic Burden of Thalassemia Major in Iran, 2015.

Authors:  Firooz Esmaeilzadeh; Azita Azarkeivan; Sara Emamgholipour; Ali Akbari Sari; Mehdi Yaseri; Batoul Ahmadi; Mohtasham Ghaffari
Journal:  J Res Health Sci       Date:  2016
  4 in total

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