Literature DB >> 2564746

The use of flumazenil (Anexate, Ro 15-1788) in the management of drug overdose.

B J Pollard1, A P Masters, P Bunting.   

Abstract

This is a report of a large selfadministered overdose of temazepam and meprobamate. The administration of flumazenil (Ro 15-1788) led to the partial antagonism of the depressant action of the drugs which was sufficient to avoid the need for invasive respiratory and cardiovascular support.

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Year:  1989        PMID: 2564746     DOI: 10.1111/j.1365-2044.1989.tb11164.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  3 in total

Review 1.  A risk-benefit assessment of flumazenil in the management of benzodiazepine overdose.

Authors:  A A Weinbroum; R Flaishon; P Sorkine; O Szold; V Rudick
Journal:  Drug Saf       Date:  1997-09       Impact factor: 5.606

Review 2.  The use of flumazenil in the management of acute drug poisoning--a review.

Authors:  A Weinbroum; P Halpern; E Geller
Journal:  Intensive Care Med       Date:  1991       Impact factor: 17.440

3.  Flumazenil antagonizes the suppressive effect of midazolam on the somatosensory evoked potentials in the rat.

Authors:  N Suzuki; Y Hirose; N Katakura; Y Kubota
Journal:  Anesth Prog       Date:  1991 Jan-Feb
  3 in total

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