Literature DB >> 25647080

Two new flavonoids from the roots of Scutellaria baicalensis.

Hai-Lin Long1, Guo-Ying Xu, An-Jun Deng, Zhi-Hong Li, Lin Ma, Yao Lu, Zhi-Hui Zhang, Feng Wu, Hai-Lin Qin.   

Abstract

One new flavone, 5,7-dihydroxy-8,2',3',6'-tetramethoxyflavone (1), and one new flavonol, 5,7,6'-trihydroxy-2'-methoxyflavonol (2), were isolated from the roots of Scutellaria baicalensis, and their structures were elucidated on the basis of extensive spectroscopic evidences, especially 1D and 2D NMR and HR-ESI-MS experiments. The structure features of these new compounds lie in the substitution at both C-2' and C-6' positions of B-ring by hydroxyl or methoxyl groups.

Entities:  

Keywords:  5,7,6′-trihydroxy-2′-methoxyflavonol; 5,7-dihydroxy-8,2′,3′,6′-tetramethoxyflavone; Labiatae; Scutellaria baicalensis; flavonoids

Mesh:

Substances:

Year:  2015        PMID: 25647080     DOI: 10.1080/10286020.2014.999048

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  4 in total

1.  Three new lignan glucosides from the roots of Scutellaria baicalensis.

Authors:  Hailin Long; Haijing Zhang; Anjun Deng; Lin Ma; Lianqiu Wu; Zhihong Li; Zhihui Zhang; Wenjie Wang; Jiandong Jiang; Hailin Qin
Journal:  Acta Pharm Sin B       Date:  2016-04-18       Impact factor: 11.413

Review 2.  A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis.

Authors:  Zi-Long Wang; Shuang Wang; Yi Kuang; Zhi-Min Hu; Xue Qiao; Min Ye
Journal:  Pharm Biol       Date:  2018-12       Impact factor: 3.503

Review 3.  Phytochemical Profiling and Bio-Potentiality of Genus Scutellaria: Biomedical Approach.

Authors:  Muddaser Shah; Sidra Mubin; Syed Shams Ul Hassan; Priti Tagde; Obaid Ullah; Md Habibur Rahman; Ahmed Al-Harrasi; Najeeb Ur Rehman; Waheed Murad
Journal:  Biomolecules       Date:  2022-07-04

4.  An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (Mpro) of SARS-COV-2 from crude natural extracts.

Authors:  Giovanna Baron; Sofia Borella; Larissa Della Vedova; Serena Vittorio; Giulio Vistoli; Marina Carini; Giancarlo Aldini; Alessandra Altomare
Journal:  Talanta       Date:  2022-08-12       Impact factor: 6.556

  4 in total

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