| Literature DB >> 25645264 |
Ying Xie1, Hongjie Pan, Mao Liu, Xiao Xiao, Yian Shi.
Abstract
Transamination of α-keto acids with transaminases and pyridoxamine phosphate is an important process to form optically active α-amino acids in biological systems. Various biomimetic transamination systems have been developed for carbonyl compounds including α-keto acid derivatives, fluoroalkyl ketones, and unactivated ketones with chiral vitamin B6 analogues, artificial transaminase mimics, chiral nitrogen sources, and chiral catalysts. This review provides a brief summary of this area.Entities:
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Year: 2015 PMID： 25645264 DOI： 10.1039/c4cs00507d
Source DB: PubMed Journal: Chem Soc Rev ISSN： 0306-0012 Impact factor: 54.564