Literature DB >> 2564509

Polymerase chain reaction for detection of dissemination in gastric lymphoma.

D Cunningham1, T Hickish, R D Rosin, P Sauven, J H Baron, P J Farrell, P Isaacson.   

Abstract

The polymerase chain reaction (PCR) was used to detect malignant lymphoma cells with the bcl-2 gene rearrangement in the peritoneal washings and bone marrow of a patient with an apparently localised gastric lymphoma. After four courses of cytotoxic drug treatment the cells could no longer be detected in either site. PCR is a useful addition to the staging investigations of non-Hodgkin lymphoma and can also be used to monitor response to treatment.

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Year:  1989        PMID: 2564509     DOI: 10.1016/s0140-6736(89)92208-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  6 in total

Review 1.  Molecular biology in medicine.

Authors:  B D Young
Journal:  Postgrad Med J       Date:  1992-04       Impact factor: 2.401

Review 2.  Update on gastric lymphoma.

Authors:  C R Thomas
Journal:  J Natl Med Assoc       Date:  1991-08       Impact factor: 1.798

3.  The bcl-2 gene in primary B cell lymphoma of mucosa-associated lymphoid tissue (MALT).

Authors:  L Pan; T C Diss; D Cunningham; P G Isaacson
Journal:  Am J Pathol       Date:  1989-07       Impact factor: 4.307

4.  Relationship between high-grade lymphoma and low-grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomach.

Authors:  J K Chan; C S Ng; P G Isaacson
Journal:  Am J Pathol       Date:  1990-05       Impact factor: 4.307

5.  Familial primary gastric lymphoma.

Authors:  D Hayoz; M Extermann; B F Odermatt; P Pugin; C Regamey; H Knecht
Journal:  Gut       Date:  1993-01       Impact factor: 23.059

6.  Molecular monitoring of low grade non-Hodgkin's lymphoma by gene amplification.

Authors:  T F Hickish; H Purvies; J Mansi; M Soukop; D Cunningham
Journal:  Br J Cancer       Date:  1991-12       Impact factor: 7.640

  6 in total

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