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Literature DB >> 25644972

Protein engineering in the 21st century.

Roberto A Chica¹.

Abstract

Keywords: Computational protein design; Enzymes; Protein NMR; Protein folding; Protein-peptide interactions

Mesh：

Year: 2015 PMID： 25644972 PMCID： PMC4380975 DOI： 10.1002/pro.2656

Source DB: PubMed Journal: Protein Sci ISSN： 0961-8368 Impact factor: 6.725

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13 in total

1. Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase.

Authors: Jennifer M Axe; Kathleen F O'Rourke; Nicole E Kerstetter; Eric M Yezdimer; Yan M Chan; Alexander Chasin; David D Boehr
Journal: Protein Sci Date: 2014-12-11 Impact factor: 6.725

2. Design of an allosterically regulated retroaldolase.

Authors: Elizabeth A Raymond; Korrie L Mack; Jennifer H Yoon; Olesia V Moroz; Yurii S Moroz; Ivan V Korendovych
Journal: Protein Sci Date: 2015-01-13 Impact factor: 6.725

3. Vibrational entropy differences between mesophile and thermophile proteins and their use in protein engineering.

Authors: Vincent Frappier; Rafael Najmanovich
Journal: Protein Sci Date: 2014-11-05 Impact factor: 6.725

4. Rapid search for tertiary fragments reveals protein sequence-structure relationships.

Authors: Jianfu Zhou; Gevorg Grigoryan
Journal: Protein Sci Date: 2014-12-31 Impact factor: 6.725

5. Protein unfolding rates correlate as strongly as folding rates with native structure.

Authors: Aron Broom; Shachi Gosavi; Elizabeth M Meiering
Journal: Protein Sci Date: 2014-12-26 Impact factor: 6.725

6. Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.

Authors: Tracy R Clinton; Matthew T Weinstock; Michael T Jacobsen; Nicolas Szabo-Fresnais; Maya J Pandya; Frank G Whitby; Andrew S Herbert; Laura I Prugar; Rena McKinnon; Christopher P Hill; Brett D Welch; John M Dye; Debra M Eckert; Michael S Kay
Journal: Protein Sci Date: 2014-10-31 Impact factor: 6.725

Protein engineering in the 21st century.

1. Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase.

2. Design of an allosterically regulated retroaldolase.

3. Vibrational entropy differences between mesophile and thermophile proteins and their use in protein engineering.

4. Rapid search for tertiary fragments reveals protein sequence-structure relationships.

5. Protein unfolding rates correlate as strongly as folding rates with native structure.

6. Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.

7. Computational de novo design of a four-helix bundle protein--DND_4HB.

8. Increasing the affinity of selective bZIP-binding peptides through surface residue redesign.

9. Network of long-range concerted chemical shift displacements upon ligand binding to human angiogenin.

10. Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease.

Review 1. Droplet Microfluidics-Enabled High-Throughput Screening for Protein Engineering.