| Literature DB >> 25644811 |
Chao Liu1, Zhangxin Yu2, Fujun Wang2, Xing Zhong2, Li Jiang2, Feifei Zhang2, Yinxia Tang2, Zhaohua Yan2, Su Zeng3, Tong Pu4.
Abstract
A brand-new impurity was detected by RP-HPLC in the prasugrel. The impurity was named as Impurity X. Impurity X was isolated by using semi-preparative HPLC followed by characterization using nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry. The functional mechanism of Impurity X was speculated. Impurity X could be controlled in the manufacture process of the prasugrel active pharmaceutical ingredient effectively.Mesh：
Substances：
Year: 2015 PMID： 25644811 DOI： 10.1093/chromsci/bmu211
Source DB: PubMed Journal: J Chromatogr Sci ISSN： 0021-9665 Impact factor: 1.618