Literature DB >> 25643675

[Polypharmacy prevalence and potentially inappropriate drug prescription in the elderly hospitalized for cardiovascular disease].

José Luis Martínez-Arroyo1, Alejandro Gómez-García2, Demetrio Sauceda-Martínez1.   

Abstract

INTRODUCTION: Many older adults have multiple medical conditions that require medical attention, exposing them to polypharmacy and to a higher increase in prescribing potentially inappropriate medications. These situations may cause adverse drug reactions, longer hospital stays, and death. The prevalence of polypharmacy in our country is estimated at 55% and inappropriate prescribing of medications of 30%.
OBJECTIVE: To determine the prevalence of polypharmacy and potentially inappropriate drug prescription in older patients hospitalized for cardiovascular diseases.
MATERIAL AND METHODS: Patients older than 70 years from a tertiary level hospital admitted to cardiology and angiology were included, from the period 2013-2014. Fragility status, polypharmacy, and drug prescription based on the Beer's criteria were established. The results were analyzed using descriptive statistics. For inferential analysis, cross tabulations with Pearson χ2 were used.
RESULTS: 446 patients where included, with female predominance of 56% (mean age 76.6 ± 5.9 years). The prevalence of fragility was 35.7%, polypharmacy 84.5%, and inappropriate prescription of drugs 48.9%. Coefficient correlation between inappropriate prescription of drugs and polypharmacy was p = 0.001.
CONCLUSIONS: The prevalence of polypharmacy and inappropriate prescription of drugs was higher than reported previously, which shows the situational diagnosis in this tertiary level hospital, considering a population with high cardiovascular risk.

Entities:  

Year:  2014        PMID: 25643675

Source DB:  PubMed          Journal:  Gac Med Mex        ISSN: 0016-3813            Impact factor:   0.302


  3 in total

1.  Prevalence and Covariates of Polypharmacy in Elderly Patients on Discharge from a Tertiary 
Care Hospital in Oman.

Authors:  Amna Al-Hashar; Hamed Al Sinawi; Anwar Al Mahrizi; Manal Al-Hatrushi
Journal:  Oman Med J       Date:  2016-11

2.  Risk factors for developing drug-related problems in patients with cardiovascular diseases attending Gondar University Hospital, Ethiopia.

Authors:  Ousman Abubeker Abdela; Akshaya Srikanth Bhagavathula; Henok Getachew; Yohannes Kelifa
Journal:  J Pharm Bioallied Sci       Date:  2016 Oct-Dec

3.  Medication Appropriateness, Polypharmacy, and Drug-Drug Interactions in Ambulatory Elderly Patients with Cardiovascular Diseases at Tikur Anbessa Specialized Hospital, Ethiopia.

Authors:  Limi Adem; Gobezie T Tegegne
Journal:  Clin Interv Aging       Date:  2022-04-16       Impact factor: 3.829

  3 in total

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