| Literature DB >> 2564345 |
R D Pearce1, D Kiehm, D T Armstrong, P B Little, J W Callahan, L R Klunder, J T Clarke.
Abstract
Intraperitoneal injection of allogeneic liver cells from 43-day-old male fetuses into normal 60-day female goat fetuses resulted in persistent hemopoietic chimerism in surviving recipients without clinical evidence of graft-versus-host disease. Transplantation of normal fetal liver cells into preimmunocompetent goat fetuses affected with beta-D-mannosidosis may provide an alternative strategy for evaluating hemopoietic stem cell transplantation in the treatment of human lysosomal storage diseases.Entities:
Mesh:
Year: 1989 PMID: 2564345 DOI: 10.1007/BF01951819
Source DB: PubMed Journal: Experientia ISSN: 0014-4754