Literature DB >> 25642961

DNA repair: Familiar ends with alternative endings.

Nam Woo Cho1, Roger A Greenberg1.   

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Year:  2015        PMID： 25642961     DOI： 10.1038/nature14200

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  11 in total

1.  Rag mutations reveal robust alternative end joining.

Authors:  Barbara Corneo; Rebecca L Wendland; Ludovic Deriano; Xiaoping Cui; Isaac A Klein; Serre-Yu Wong; Suzzette Arnal; Abigail J Holub; Geoffrey R Weller; Bette A Pancake; Sundeep Shah; Vicky L Brandt; Katheryn Meek; David B Roth
Journal:  Nature       Date:  2007-09-27       Impact factor: 49.962

2.  Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.

Authors:  Pedro A Mateos-Gomez; Fade Gong; Nidhi Nair; Kyle M Miller; Eros Lazzerini-Denchi; Agnel Sfeir
Journal:  Nature       Date:  2015-02-02       Impact factor: 49.962

3.  Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways.

Authors:  S J Boulton; S P Jackson
Journal:  EMBO J       Date:  1996-09-16       Impact factor: 11.598

4.  IgH class switching and translocations use a robust non-classical end-joining pathway.

Authors:  Catherine T Yan; Cristian Boboila; Ellen Kris Souza; Sonia Franco; Thomas R Hickernell; Michael Murphy; Sunil Gumaste; Mark Geyer; Ali A Zarrin; John P Manis; Klaus Rajewsky; Frederick W Alt
Journal:  Nature       Date:  2007-08-22       Impact factor: 49.962

5.  Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions.

Authors:  Amy Marie Yu; Mitch McVey
Journal:  Nucleic Acids Res       Date:  2010-05-11       Impact factor: 19.160

6.  Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.

Authors:  Helen E Bryant; Niklas Schultz; Huw D Thomas; Kayan M Parker; Dan Flower; Elena Lopez; Suzanne Kyle; Mark Meuth; Nicola J Curtin; Thomas Helleday
Journal:  Nature       Date:  2005-04-14       Impact factor: 69.504

7.  Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.

Authors:  Tatiana Kent; Gurushankar Chandramouly; Shane Michael McDevitt; Ahmet Y Ozdemir; Richard T Pomerantz
Journal:  Nat Struct Mol Biol       Date:  2015-02-02       Impact factor: 15.369

8.  Mutational processes molding the genomes of 21 breast cancers.

Authors:  Serena Nik-Zainal; Ludmil B Alexandrov; David C Wedge; Peter Van Loo; Christopher D Greenman; Keiran Raine; David Jones; Jonathan Hinton; John Marshall; Lucy A Stebbings; Andrew Menzies; Sancha Martin; Kenric Leung; Lina Chen; Catherine Leroy; Manasa Ramakrishna; Richard Rance; King Wai Lau; Laura J Mudie; Ignacio Varela; David J McBride; Graham R Bignell; Susanna L Cooke; Adam Shlien; John Gamble; Ian Whitmore; Mark Maddison; Patrick S Tarpey; Helen R Davies; Elli Papaemmanuil; Philip J Stephens; Stuart McLaren; Adam P Butler; Jon W Teague; Göran Jönsson; Judy E Garber; Daniel Silver; Penelope Miron; Aquila Fatima; Sandrine Boyault; Anita Langerød; Andrew Tutt; John W M Martens; Samuel A J R Aparicio; Åke Borg; Anne Vincent Salomon; Gilles Thomas; Anne-Lise Børresen-Dale; Andrea L Richardson; Michael S Neuberger; P Andrew Futreal; Peter J Campbell; Michael R Stratton
Journal:  Cell       Date:  2012-05-17       Impact factor: 41.582

9.  Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.

Authors:  Hannah Farmer; Nuala McCabe; Christopher J Lord; Andrew N J Tutt; Damian A Johnson; Tobias B Richardson; Manuela Santarosa; Krystyna J Dillon; Ian Hickson; Charlotte Knights; Niall M B Martin; Stephen P Jackson; Graeme C M Smith; Alan Ashworth
Journal:  Nature       Date:  2005-04-14       Impact factor: 69.504

10.  Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.

Authors:  Raphael Ceccaldi; Jessica C Liu; Ravindra Amunugama; Ildiko Hajdu; Benjamin Primack; Mark I R Petalcorin; Kevin W O'Connor; Panagiotis A Konstantinopoulos; Stephen J Elledge; Simon J Boulton; Timur Yusufzai; Alan D D'Andrea
Journal:  Nature       Date:  2015-02-02       Impact factor: 69.504
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  6 in total

Review 1.  DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity.

Authors:  Xiaojiang S Chen; Richard T Pomerantz
Journal:  Genes (Basel)       Date:  2021-07-27       Impact factor: 4.096

2.  Mechanistic Modelling and Bayesian Inference Elucidates the Variable Dynamics of Double-Strand Break Repair.

Authors:  Mae L Woods; Chris P Barnes
Journal:  PLoS Comput Biol       Date:  2016-10-14       Impact factor: 4.475

3.  Dual loss of human POLQ and LIG4 abolishes random integration.

Authors:  Shinta Saito; Ryo Maeda; Noritaka Adachi
Journal:  Nat Commun       Date:  2017-07-11       Impact factor: 14.919

4.  Clinical values of Ku80 upregulation in superficial esophageal squamous cell carcinoma.

Authors:  Shuai Wang; Junjie Xi; Zongwu Lin; Jiatao Hao; Can Yao; Cheng Zhan; Wei Jiang; Yu Shi; Qun Wang
Journal:  Cancer Med       Date:  2018-03-13       Impact factor: 4.452

5.  DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres.

Authors:  Atsushi T Onaka; Jie Su; Yasuhiro Katahira; Crystal Tang; Faria Zafar; Keita Aoki; Wataru Kagawa; Hironori Niki; Hiroshi Iwasaki; Takuro Nakagawa
Journal:  Commun Biol       Date:  2020-04-30

6.  The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.

Authors:  Veronika Mladenova; Emil Mladenov; Shipra Chaudhary; Martin Stuschke; George Iliakis
Journal:  Front Cell Dev Biol       Date:  2022-10-03
  6 in total

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