Literature DB >> 2564045

Apparent non-involvement of prions in the pathogenesis of spongiform change in HIV-infected brain.

P N Goldwater1, J C Paton.   

Abstract

Characteristic neuropathological white matter changes in the brains of patients dying from the acquired immune deficiency syndrome (AIDS) suggest pathogenetic involvement of either the PrP27-30 gene or a scrapie-related prion; however, proteinase-K resistant scrapie-like proteins could not be detected in brain tissue from AIDS patients.

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Year:  1989        PMID: 2564045     DOI: 10.1097/00005072-198903000-00005

Source DB:  PubMed          Journal:  J Neuropathol Exp Neurol        ISSN: 0022-3069            Impact factor:   3.685


  2 in total

Review 1.  The ubiquitin-proteasome system in spongiform degenerative disorders.

Authors:  Brandi R Whatley; Lian Li; Lih-Shen Chin
Journal:  Biochim Biophys Acta       Date:  2008-08-23

2.  Vacuolating encephalitis in mice infected by human coronavirus OC43.

Authors:  Hélène Jacomy; Pierre J Talbot
Journal:  Virology       Date:  2003-10-10       Impact factor: 3.616

  2 in total

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