Literature DB >> 2563977

Immunohistochemical localization of glutamine synthetase in human liver.

R Gebhardt1, H Schmid, H Fitzke.   

Abstract

Glutamine synthetase (GS) of human liver was recognized with a polyclonal antibody to pig brain GS, but failed to stain with an antibody against rat liver GS. Using the latter antibody GS of human liver was shown to be localized within small rings of 1 to 3 hepatocytes surrounding the terminal hepatic venules. This pattern was analogous to that seen in rat and mouse liver.

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Year:  1989        PMID： 2563977     DOI： 10.1007/BF01954848

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

2.  Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver.

Authors:  D D Smith; J W Campbell
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

3.  Heterogeneous distribution of glutamine synthetase during rat liver development.

Authors:  J W Gaasbeek Janzen; R Gebhardt; G H ten Voorde; W H Lamers; R Charles; A F Moorman
Journal:  J Histochem Cytochem       Date:  1987-01       Impact factor: 2.479

4.  Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle.

Authors:  D Häussinger; H Sies; W Gerok
Journal:  J Hepatol       Date:  1985       Impact factor: 25.083

5.  Reciprocal regulation of glutamine synthetase and carbamoylphosphate synthetase levels in rat liver.

Authors:  C J de Groot; G H ten Voorde; R E van Andel; A te Kortschot; J W Gaasbeek Janzen; R H Wilson; A F Moorman; R Charles; W H Lamers
Journal:  Biochim Biophys Acta       Date:  1987-04-29

6.  Specific chromosomal abnormalities characterize four established cell lines derived from malignant human gliomas.

Authors:  S H Bigner; H S Friedman; J A Biegel; C J Wikstrand; J Mark; R Gebhardt; L F Eng; D D Bigner
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

7.  Alterations of hepatic enzyme levels and of the acinar distribution of glutamine synthetase in response to experimental liver injury in the rat.

Authors:  R Gebhardt; H J Burger; H Heini; K L Schreiber; D Mecke
Journal:  Hepatology       Date:  1988 Jul-Aug       Impact factor: 17.425

8.  Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.

Authors:  R Gebhardt; D Mecke
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

9.  Acquisition of antigens characteristic of adult pericentral hepatocytes by differentiating fetal hepatoblasts in vitro.

Authors:  A L Bennett; K E Paulson; R E Miller; J E Darnell
Journal:  J Cell Biol       Date:  1987-09       Impact factor: 10.539
  9 in total
  2 in total

1.  The stem cells of the liver--a selective review.

Authors:  K Aterman
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  Subpopulations of rat hepatocytes separated by Percoll density-gradient centrifugation show characteristics consistent with different acinar locations.

Authors:  J C Osypiw; R L Allen; D Billington
Journal:  Biochem J       Date:  1994-12-01       Impact factor: 3.857
  2 in total

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