Literature DB >> 25639596

Carnosic acid.

Simona Birtić1, Pierre Dussort2, François-Xavier Pierre2, Antoine C Bily2, Marc Roller2.   

Abstract

Carnosic acid (salvin), which possesses antioxidative and antimicrobial properties, is increasingly exploited within the food, nutritional health and cosmetics industries. Since its first extraction from a Salvia species (∼70 years ago) and its identification (∼50 years ago), numerous articles and patents (∼400) have been published on specific food and medicinal applications of Rosmarinus and Salvia plant extracts abundant in carnosic acid. In contrast, relevant biochemical, physiological or molecular studies in planta have remained rare. In this overview, recent advances in understanding of carnosic acid distribution, biosynthesis, accumulation and role in planta, and its applications are summarised. We also discuss the deficiencies in our understanding of the relevant biochemical processes, and suggest the molecular targets of carnosic acid. Finally, future perspectives and studies related to its potential roles are highlighted.
Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Antimicrobial; Antioxidant; Carnosic acid; Labiatae; Lamiaceae; Oxidation; Photooxidation; Photoprotection; Rosemary; Rosmarinus officinalis; Sage; Salvia

Mesh:

Substances:

Year:  2015        PMID: 25639596     DOI: 10.1016/j.phytochem.2014.12.026

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  62 in total

1.  BRAF signals to pro-apoptotic BIM to enhance AraC cytotoxicity induced in AML cells by Vitamin D-based differentiation agents.

Authors:  Xuening Wang; Jonathan S Harrison; George P Studzinski
Journal:  J Steroid Biochem Mol Biol       Date:  2016-09-13       Impact factor: 4.292

2.  Carnosic Acid and Carnosol, Two Major Antioxidants of Rosemary, Act through Different Mechanisms.

Authors:  Margot Loussouarn; Anja Krieger-Liszkay; Ljubica Svilar; Antoine Bily; Simona Birtić; Michel Havaux
Journal:  Plant Physiol       Date:  2017-09-15       Impact factor: 8.340

3.  Carnosic Acid Affords Mitochondrial Protection in Chlorpyrifos-Treated Sh-Sy5y Cells.

Authors:  Marcos Roberto de Oliveira; Alessandra Peres; Gustavo Costa Ferreira; Patrícia Fernanda Schuck; Simone Morelo Dal Bosco
Journal:  Neurotox Res       Date:  2016-04-15       Impact factor: 3.911

Review 4.  Rosemary (Rosmarinus officinalis) as a potential therapeutic plant in metabolic syndrome: a review.

Authors:  Faezeh Vahdati Hassani; Kobra Shirani; Hossein Hosseinzadeh
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-05-13       Impact factor: 3.000

5.  Carnosic acid biosynthesis elucidated by a synthetic biology platform.

Authors:  Codruta Ignea; Anastasia Athanasakoglou; Efstathia Ioannou; Panagiota Georgantea; Fotini A Trikka; Sofia Loupassaki; Vassilios Roussis; Antonios M Makris; Sotirios C Kampranis
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-14       Impact factor: 11.205

Review 6.  Carnosic Acid as a Promising Agent in Protecting Mitochondria of Brain Cells.

Authors:  Marcos Roberto de Oliveira
Journal:  Mol Neurobiol       Date:  2018-01-15       Impact factor: 5.590

Review 7.  The Quest for Phenolic Compounds from Macroalgae: A Review of Extraction and Identification Methodologies.

Authors:  Sónia A O Santos; Rafael Félix; Adriana C S Pais; Sílvia M Rocha; Armando J D Silvestre
Journal:  Biomolecules       Date:  2019-12-09

8.  Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss.

Authors:  Zu-Guo Zheng; Hui-Min Cheng; Ya-Ping Zhou; Si-Tong Zhu; Pyone Myat Thu; Hui-Jun Li; Ping Li; Xiaojun Xu
Journal:  Cell Death Differ       Date:  2020-01-06       Impact factor: 15.828

Review 9.  The Dietary Components Carnosic Acid and Carnosol as Neuroprotective Agents: a Mechanistic View.

Authors:  Marcos Roberto de Oliveira
Journal:  Mol Neurobiol       Date:  2015-11-09       Impact factor: 5.590

Review 10.  Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery.

Authors:  Gina Porras; François Chassagne; James T Lyles; Lewis Marquez; Micah Dettweiler; Akram M Salam; Tharanga Samarakoon; Sarah Shabih; Darya Raschid Farrokhi; Cassandra L Quave
Journal:  Chem Rev       Date:  2020-11-09       Impact factor: 60.622

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