Jianhui Zhang1, Xiaolei Kang2. 1. Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China. Electronic address: Zhangjh1220@163.com. 2. Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
Abstract
BACKGROUND: Plastic bronchitis (PB) is a rare disease characterized by formation of bronchial casts. It is usually associated with congenital heart disease, sickle cell disease, lymphoma, and lung diseases such as asthma and pneumonia. OBJECTIVES: To report 14 cases of PB with influenza A or influenza B infection. METHODS: We analyzed the clinical manifestations, bronchoscopic and histologic findings, clinical courses, and outcomes. RESULTS: These cases indicate that PB is a life-threatening complication of severe influenza. Plastic bronchitis should be considered in the diagnosis of children with acute respiratory distress such as lung atelectasis accompanied by influenza. CONCLUSIONS: Diagnosis should be made by bronchial endoscopy and histopathology, and bronchial casts removed as early as possible.
BACKGROUND: Plastic bronchitis (PB) is a rare disease characterized by formation of bronchial casts. It is usually associated with congenital heart disease, sickle cell disease, lymphoma, and lung diseases such as asthma and pneumonia. OBJECTIVES: To report 14 cases of PB with influenza A or influenza B infection. METHODS: We analyzed the clinical manifestations, bronchoscopic and histologic findings, clinical courses, and outcomes. RESULTS: These cases indicate that PB is a life-threatening complication of severe influenza. Plastic bronchitis should be considered in the diagnosis of children with acute respiratory distress such as lung atelectasis accompanied by influenza. CONCLUSIONS: Diagnosis should be made by bronchial endoscopy and histopathology, and bronchial casts removed as early as possible.
Authors: Michael A Pritchett; Catherine L Oberg; Adam Belanger; Jose De Cardenas; George Cheng; Gustavo Cumbo Nacheli; Carlos Franco-Paredes; Jaspal Singh; Jennifer Toth; Michael Zgoda; Erik Folch Journal: J Thorac Dis Date: 2020-05 Impact factor: 3.005