Literature DB >> 25637255

CD103+ γδ T cell large granular lymphocytosis in a patient with refractory celiac disease: a diagnostic enigma.

Sreejesh Sreedharanunni1, Neelam Varma, Man Updesh Singh Sachdeva, Kirti Gupta, Rekha Pai, Rakesh Kochhar, Pankaj Malhotra, Subhash Varma.   

Abstract

Indolent γδ T cell lymphomas/leukemias are rare and overlap with the morphological spectrum of large granular lymphocyte (LGL) leukemia. We report an extremely rare case of CD103(+) γδ T LGL leukemia in a patient with celiac disease who presented with refractory diarrhea. Whether the refractory diarrhea in our patient was a manifestation of LGL leukemia itself or whether the clonal LGL expansion is a manifestation of refractory celiac disease (RCD) remains an enigma. This report highlights the diagnostic difficulties and the need of consensus in categorizing clonal CD103(+) lymphocytosis in patients with RCD.

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Year:  2015        PMID: 25637255     DOI: 10.1007/s12185-015-1736-x

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  18 in total

Review 1.  Classification and management of refractory coeliac disease.

Authors:  Alberto Rubio-Tapia; Joseph A Murray
Journal:  Gut       Date:  2010-04       Impact factor: 23.059

2.  Immunophenotypic attributes of benign peripheral blood gammadelta T cells and conditions associated with their increase.

Authors:  Anja C Roden; William G Morice; Curtis A Hanson
Journal:  Arch Pathol Lab Med       Date:  2008-11       Impact factor: 5.534

3.  Large granular lymphocytic leukemia: a treatable form of refractory celiac disease.

Authors:  Georgia Malamut; Bertrand Meresse; Virginie Verkarre; Sophie Kaltenbach; Nicolas Montcuquet; Jean-Paul Duong Van Huyen; Céline Callens; Julien Lenglet; Gabriel Rahmi; Elia Samaha; Brigitte Ranque; Elizabeth Macintyre; Isabelle Radford-Weiss; Olivier Hermine; Nadine Cerf-Bensussan; Christophe Cellier
Journal:  Gastroenterology       Date:  2012-08-23       Impact factor: 22.682

Review 4.  Guidelines for the management of mature T-cell and NK-cell neoplasms (excluding cutaneous T-cell lymphoma).

Authors:  Claire E Dearden; Rod Johnson; Ruth Pettengell; Stephen Devereux; Kate Cwynarski; Sean Whittaker; Andrew McMillan
Journal:  Br J Haematol       Date:  2011-04-11       Impact factor: 6.998

5.  A monoclonal antibody (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes.

Authors:  N Cerf-Bensussan; A Jarry; N Brousse; B Lisowska-Grospierre; D Guy-Grand; C Griscelli
Journal:  Eur J Immunol       Date:  1987-09       Impact factor: 5.532

6.  Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders.

Authors:  Girish Venkataraman; Christine Aguhar; Robert J Kreitman; Constance M Yuan; Maryalice Stetler-Stevenson
Journal:  Am J Clin Pathol       Date:  2011-10       Impact factor: 2.493

7.  Gastrointestinal T cell lymphoma: predominant cytotoxic phenotypes, including alpha/beta, gamma/delta T cell and natural killer cells.

Authors:  A Katoh; K Ohshima; M Kanda; S Haraoka; M Sugihara; J Suzumiya; C Kawasaki; K Shimazaki; S Ikeda; M Kikuchi
Journal:  Leuk Lymphoma       Date:  2000-09

8.  Are complicated forms of celiac disease cryptic T-cell lymphomas?

Authors:  F Carbonnel; L Grollet-Bioul; J C Brouet; M F Teilhac; J Cosnes; R Angonin; M Deschaseaux; F P Châtelet; J P Gendre; F Sigaux
Journal:  Blood       Date:  1998-11-15       Impact factor: 22.113

9.  Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.

Authors:  Audrey Le Floc'h; Abdelali Jalil; Isabelle Vergnon; Béatrice Le Maux Chansac; Vladimir Lazar; Georges Bismuth; Salem Chouaib; Fathia Mami-Chouaib
Journal:  J Exp Med       Date:  2007-02-26       Impact factor: 14.307

10.  Essential role for CD103 in the T cell-mediated regulation of experimental colitis.

Authors:  Oliver Annacker; Janine L Coombes; Vivianne Malmstrom; Holm H Uhlig; Tim Bourne; Bengt Johansson-Lindbom; William W Agace; Christina M Parker; Fiona Powrie
Journal:  J Exp Med       Date:  2005-10-10       Impact factor: 14.307

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  1 in total

1.  CD103+ Dendritic Cells Elicit CD8+ T Cell Responses to Accelerate Kidney Injury in Adriamycin Nephropathy.

Authors:  Qi Cao; Junyu Lu; Qing Li; Changqi Wang; Xin Maggie Wang; Vincent W S Lee; Chengshi Wang; Hanh Nguyen; Guoping Zheng; Ye Zhao; Stephen I Alexander; Yiping Wang; David C H Harris
Journal:  J Am Soc Nephrol       Date:  2015-09-16       Impact factor: 10.121

  1 in total

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