Literature DB >> 25636147

Skeletal diversity from carbohydrates: use of mannose for the diversity-oriented synthesis of polyhydroxylated compounds.

Elena Lenci1, Gloria Menchi, Antonio Guarna, Andrea Trabocchi.   

Abstract

The application of d-mannose as a multipurpose building block from the chiral pool enabled the diversity-oriented synthesis of an array of cyclic and bicyclic scaffolds with polyhydroxylated appendages with the aim to expand the skeletal diversity in the panorama of glycopeptidomimetic compounds.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25636147     DOI： 10.1021/jo502701c

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Diversity-Oriented Synthesis of Natural-Product-like Libraries Containing a 3-Methylbenzofuran Moiety for the Discovery of New Chemical Elicitors.

Authors:  Xingrui He; Xia Chen; Songbo Lin; Xiaochang Mo; Pengyong Zhou; Zhihao Zhang; Yaoyao Lu; Yu Yang; Haining Gu; Zhicai Shang; Yonggen Lou; Jun Wu
Journal:  ChemistryOpen       Date:  2016-12-09       Impact factor: 2.911

2.  Identification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library.

Authors:  Elena Lenci; Riccardo Innocenti; Alessio Biagioni; Gloria Menchi; Francesca Bianchini; Andrea Trabocchi
Journal:  Molecules       Date:  2016-10-20       Impact factor: 4.411

3.  Diversity-Oriented Synthesis and Chemoinformatic Analysis of the Molecular Diversity of sp3-Rich Morpholine Peptidomimetics.

Authors:  Elena Lenci; Riccardo Innocenti; Gloria Menchi; Andrea Trabocchi
Journal:  Front Chem       Date:  2018-10-30       Impact factor: 5.221

Review 4.  Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections.

Authors:  Sarah L Kidd; Thomas J Osberger; Natalia Mateu; Hannah F Sore; David R Spring
Journal:  Front Chem       Date:  2018-10-16       Impact factor: 5.221

5.  C-Linked Glycomimetic Libraries Accessed by the Passerini Reaction.

Authors:  Kristina Vlahoviček-Kahlina; Josipa Suć Sajko; Ivanka Jerić
Journal:  Int J Mol Sci       Date:  2019-12-10       Impact factor: 5.923
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.