Literature DB >> 25635522

Direct arylation of sydnones with aryl chlorides toward highly substituted pyrazoles.

Andrew W Brown1, Joseph P A Harrity.   

Abstract

The direct arylation of the C4 position of both N-alkyl- and N-arylsydnones with aryl/heteroaryl chlorides has been realized. The reaction is quite general and allows access to a wide range of 4-substituted sydnones. Yields of more challenging substrates can be improved through the use of aryl bromides.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25635522     DOI: 10.1021/acs.joc.5b00143

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Sydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis.

Authors:  Florin Albota; Mino R Caira; Constantin Draghici; Florea Dumitrascu; Denisa E Dumitrescu
Journal:  Beilstein J Org Chem       Date:  2016-11-23       Impact factor: 2.883

Review 2.  [3 + 2]-Cycloaddition reaction of sydnones with alkynes.

Authors:  Veronika Hladíková; Jiří Váňa; Jiří Hanusek
Journal:  Beilstein J Org Chem       Date:  2018-06-05       Impact factor: 2.883

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.