Literature DB >> 25635453

Growing old with Myc.

Patrick A Carroll1, Robert N Eisenman2.   

Abstract

The Myc proto-oncogene has been intensively studied in tumorigenesis and development. A new paper in Cell reports the role of Myc as a determinant of mammalian longevity. Myc heterozygous mice exhibit extended lifespans resulting from alterations in multiple cellular processes distinct from those observed in other longevity models.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25635453      PMCID： PMC5425089          DOI： 10.1016/j.cell.2015.01.018

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

Review 1.  Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients.

Authors:  C Lee; V D Longo
Journal:  Oncogene       Date:  2011-04-25       Impact factor: 9.867

2.  Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.

Authors:  Michael Rera; Sepehr Bahadorani; Jaehyoung Cho; Christopher L Koehler; Matthew Ulgherait; Jae H Hur; William S Ansari; Thomas Lo; D Leanne Jones; David W Walker
Journal:  Cell Metab       Date:  2011-11-02       Impact factor: 27.287

3.  Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage.

Authors:  Ana Freije; Rut Molinuevo; Laura Ceballos; Marta Cagigas; Pilar Alonso-Lecue; René Rodriguez; Pablo Menendez; Daniel Aberdam; Ernesto De Diego; Alberto Gandarillas
Journal:  Cell Rep       Date:  2014-11-06       Impact factor: 9.423

4.  The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster.

Authors:  Lenora W M Loo; Julie Secombe; John T Little; Leni-Sue Carlos; Cynthia Yost; Pei-Feng Cheng; Erin M Flynn; Bruce A Edgar; Robert N Eisenman
Journal:  Mol Cell Biol       Date:  2005-08       Impact factor: 4.272

5.  Reduced expression of MYC increases longevity and enhances healthspan.

Authors:  Jeffrey W Hofmann; Xiaoai Zhao; Marco De Cecco; Abigail L Peterson; Luca Pagliaroli; Jayameenakshi Manivannan; Gene B Hubbard; Yuji Ikeno; Yongqing Zhang; Bin Feng; Xiaxi Li; Thomas Serre; Wenbo Qi; Holly Van Remmen; Richard A Miller; Kevin G Bath; Rafael de Cabo; Haiyan Xu; Nicola Neretti; John M Sedivy
Journal:  Cell       Date:  2015-01-22       Impact factor: 41.582

Review 6.  mTOR is a key modulator of ageing and age-related disease.

Authors:  Simon C Johnson; Peter S Rabinovitch; Matt Kaeberlein
Journal:  Nature       Date:  2013-01-17       Impact factor: 49.962

7.  Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

Authors:  Elisa Laurenti; Barbara Varnum-Finney; Anne Wilson; Isabel Ferrero; William E Blanco-Bose; Armin Ehninger; Paul S Knoepfler; Pei-Feng Cheng; H Robson MacDonald; Robert N Eisenman; Irwin D Bernstein; Andreas Trumpp
Journal:  Cell Stem Cell       Date:  2008-12-04       Impact factor: 24.633

Review 8.  Genetics of longevity in model organisms: debates and paradigm shifts.

Authors:  David Gems; Linda Partridge
Journal:  Annu Rev Physiol       Date:  2012-11-26       Impact factor: 19.318

9.  Myc-dependent genome instability and lifespan in Drosophila.

Authors:  Christina Greer; Moonsook Lee; Maaike Westerhof; Brandon Milholland; Rebecca Spokony; Jan Vijg; Julie Secombe
Journal:  PLoS One       Date:  2013-09-06       Impact factor: 3.240
  9 in total
  3 in total

1.  Ganoderma lucidum Exerts an Anticancer Effect on Human Osteosarcoma Cells via Suppressing the Wnt/β-Catenin Signaling Pathway.

Authors:  Qi-Hao Zhang; Qin-Xiao Hu; Da Xie; Bo Chang; Hou-Guang Miao; Yun-Guo Wang; De-Zhong Liu; Xue-Dong Li
Journal:  Integr Cancer Ther       Date:  2019 Jan-Dec       Impact factor: 3.279

Review 2.  Genes and Longevity of Lifespan.

Authors:  May Nasser Bin-Jumah; Muhammad Shahid Nadeem; Sadaf Jamal Gilani; Fahad A Al-Abbasi; Inam Ullah; Sami I Alzarea; Mohammed M Ghoneim; Sultan Alshehri; Aziz Uddin; Bibi Nazia Murtaza; Imran Kazmi
Journal:  Int J Mol Sci       Date:  2022-01-28       Impact factor: 5.923

3.  Antitumor activity of resveratrol against human osteosarcoma cells: a key role of Cx43 and Wnt/β-catenin signaling pathway.

Authors:  Da Xie; Gui-Zhou Zheng; Peng Xie; Qi-Hao Zhang; Fei-Xiang Lin; Bo Chang; Qin-Xiao Hu; Shi-Xin Du; Xue-Dong Li
Journal:  Oncotarget       Date:  2017-11-30
  3 in total

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