Literature DB >> 25634968

TMAO is both a biomarker and a renal toxin.

Alan M Fogelman1.   

Abstract

Entities:  

Keywords:  Editorials; end-stage; kidney; renal disease

Mesh:

Substances:

Year:  2015        PMID: 25634968      PMCID: PMC4366001          DOI: 10.1161/CIRCRESAHA.114.305680

Source DB:  PubMed          Journal:  Circ Res        ISSN: 0009-7330            Impact factor:   17.367


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  14 in total

1.  Gut feelings about heart failure.

Authors:  Jane A Cannon; John J V McMurray
Journal:  J Am Coll Cardiol       Date:  2014-10-27       Impact factor: 24.094

2.  Chronic kidney disease alters intestinal microbial flora.

Authors:  Nosratola D Vaziri; Jakk Wong; Madeleine Pahl; Yvette M Piceno; Jun Yuan; Todd Z DeSantis; Zhenmin Ni; Tien-Hung Nguyen; Gary L Andersen
Journal:  Kidney Int       Date:  2012-09-19       Impact factor: 10.612

3.  Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: refining the gut hypothesis.

Authors:  W H Wilson Tang; Zeneng Wang; Yiying Fan; Bruce Levison; Jennie E Hazen; Lillian M Donahue; Yuping Wu; Stanley L Hazen
Journal:  J Am Coll Cardiol       Date:  2014-10-27       Impact factor: 24.094

4.  γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.

Authors:  Robert A Koeth; Bruce S Levison; Miranda K Culley; Jennifer A Buffa; Zeneng Wang; Jill C Gregory; Elin Org; Yuping Wu; Lin Li; Jonathan D Smith; W H Wilson Tang; Joseph A DiDonato; Aldons J Lusis; Stanley L Hazen
Journal:  Cell Metab       Date:  2014-11-04       Impact factor: 27.287

5.  Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.

Authors:  W H Wilson Tang; Zeneng Wang; David J Kennedy; Yuping Wu; Jennifer A Buffa; Brendan Agatisa-Boyle; Xinmin S Li; Bruce S Levison; Stanley L Hazen
Journal:  Circ Res       Date:  2014-11-05       Impact factor: 17.367

6.  Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis.

Authors:  Marcus A Bain; Randall Faull; Gianfranco Fornasini; Robert W Milne; Allan M Evans
Journal:  Nephrol Dial Transplant       Date:  2006-01-09       Impact factor: 5.992

Review 7.  The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease.

Authors:  Hans-Joachim Anders; Kirstin Andersen; Bärbel Stecher
Journal:  Kidney Int       Date:  2013-01-16       Impact factor: 10.612

8.  Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.

Authors:  Brian J Bennett; Thomas Q de Aguiar Vallim; Zeneng Wang; Diana M Shih; Yonghong Meng; Jill Gregory; Hooman Allayee; Richard Lee; Mark Graham; Rosanne Crooke; Peter A Edwards; Stanley L Hazen; Aldons J Lusis
Journal:  Cell Metab       Date:  2013-01-08       Impact factor: 27.287

9.  Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.

Authors:  Zeneng Wang; Elizabeth Klipfell; Brian J Bennett; Robert Koeth; Bruce S Levison; Brandon Dugar; Ariel E Feldstein; Earl B Britt; Xiaoming Fu; Yoon-Mi Chung; Yuping Wu; Phil Schauer; Jonathan D Smith; Hooman Allayee; W H Wilson Tang; Joseph A DiDonato; Aldons J Lusis; Stanley L Hazen
Journal:  Nature       Date:  2011-04-07       Impact factor: 49.962

10.  Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.

Authors:  Robert A Koeth; Zeneng Wang; Bruce S Levison; Jennifer A Buffa; Elin Org; Brendan T Sheehy; Earl B Britt; Xiaoming Fu; Yuping Wu; Lin Li; Jonathan D Smith; Joseph A DiDonato; Jun Chen; Hongzhe Li; Gary D Wu; James D Lewis; Manya Warrier; J Mark Brown; Ronald M Krauss; W H Wilson Tang; Frederic D Bushman; Aldons J Lusis; Stanley L Hazen
Journal:  Nat Med       Date:  2013-04-07       Impact factor: 53.440

View more
  10 in total

1.  Effect of a chemical chaperone, tauroursodeoxycholic acid, on HDM-induced allergic airway disease.

Authors:  Jalahalli M Siddesha; Emily M Nakada; Bethany R Mihavics; Sidra M Hoffman; Gurkiranjit K Rattu; Nicolas Chamberlain; Jonathon M Cahoon; Karolyn G Lahue; Nirav Daphtary; Minara Aliyeva; David G Chapman; Dhimant H Desai; Matthew E Poynter; Vikas Anathy
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-05-06       Impact factor: 5.464

2.  Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.

Authors:  Michael C Petriello; Jessie B Hoffman; Manjula Sunkara; Banrida Wahlang; Jordan T Perkins; Andrew J Morris; Bernhard Hennig
Journal:  J Nutr Biochem       Date:  2016-04-01       Impact factor: 6.048

Review 3.  Emerging roles of xenobiotic detoxification enzymes in metabolic diseases.

Authors:  Michael C Petriello; Jessie B Hoffman; Andrew J Morris; Bernhard Hennig
Journal:  Rev Environ Health       Date:  2017-03-01       Impact factor: 3.458

Review 4.  Trimethylamine N-oxide: breathe new life.

Authors:  Saravanan Subramaniam; Craig Fletcher
Journal:  Br J Pharmacol       Date:  2017-08-30       Impact factor: 8.739

Review 5.  The gut microbiome, diet, and links to cardiometabolic and chronic disorders.

Authors:  Judith Aron-Wisnewsky; Karine Clément
Journal:  Nat Rev Nephrol       Date:  2015-11-30       Impact factor: 28.314

6.  Plasma and urinary metabolomic profiles of Down syndrome correlate with alteration of mitochondrial metabolism.

Authors:  Maria Caracausi; Veronica Ghini; Chiara Locatelli; Martina Mericio; Allison Piovesan; Francesca Antonaros; Maria Chiara Pelleri; Lorenza Vitale; Rosa Anna Vacca; Federica Bedetti; Maria Chiara Mimmi; Claudio Luchinat; Paola Turano; Pierluigi Strippoli; Guido Cocchi
Journal:  Sci Rep       Date:  2018-02-14       Impact factor: 4.379

Review 7.  Systematic review of the effects of the intestinal microbiota on selected nutrients and non-nutrients.

Authors:  Colette Shortt; Oliver Hasselwander; Alexandra Meynier; Arjen Nauta; Estefanía Noriega Fernández; Peter Putz; Ian Rowland; Jonathan Swann; Jessica Türk; Joan Vermeiren; Jean-Michel Antoine
Journal:  Eur J Nutr       Date:  2017-10-30       Impact factor: 5.614

Review 8.  Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease.

Authors:  Kamyar Kalantar-Zadeh; Shivam Joshi; Rebecca Schlueter; Joanne Cooke; Amanda Brown-Tortorici; Meghan Donnelly; Sherry Schulman; Wei-Ling Lau; Connie M Rhee; Elani Streja; Ekamol Tantisattamo; Antoney J Ferrey; Ramy Hanna; Joline L T Chen; Shaista Malik; Danh V Nguyen; Susan T Crowley; Csaba P Kovesdy
Journal:  Nutrients       Date:  2020-06-29       Impact factor: 5.717

9.  Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota.

Authors:  Junfeng Liu; Lingyun Lai; Jiajia Lin; Jiajia Zheng; Xiaoli Nie; Xiaoye Zhu; Jun Xue; Te Liu
Journal:  Int J Biol Sci       Date:  2020-01-14       Impact factor: 6.580

10.  Malodorous biogenic amines in Escherichia coli-caused urinary tract infections in women-a metabolomics approach.

Authors:  Scarlett Puebla-Barragan; Justin Renaud; Mark Sumarah; Gregor Reid
Journal:  Sci Rep       Date:  2020-06-16       Impact factor: 4.379

  10 in total

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