| Literature DB >> 25634161 |
Adam Rahman1, Syed Jafry2, Khursheed Jeejeebhoy3, A Dave Nagpal2, Barbara Pisani4, Ravi Agarwala5.
Abstract
Heart failure is a growing public health concern. Advanced heart failure is frequently associated with severe muscle wasting, termed cardiac cachexia This process is driven by systemic inflammation and tumor necrosis factor in a manner common to other forms of disease-related wasting seen with cancer or human immunodeficiency virus. A variable degree of malnutrition is often superimposed from poor nutrient intake. Cardiac cachexia significantly decreases quality of life and survival in patients with heart failure. This review outlines the evaluation of nutrition status in heart failure, explores the pathophysiology of cardiac cachexia, and discusses therapeutic interventions targeting wasting in these patients.Entities:
Keywords: cardiac disease; critical care; internal medicine; minerals/trace elements; nutrition; nutrition assessment; nutrition support practice; organ transplantation; outcomes research/quality; proteins; research and diseases; vitamins
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Year: 2015 PMID： 25634161 DOI： 10.1177/0148607114566854
Source DB: PubMed Journal: JPEN J Parenter Enteral Nutr ISSN： 0148-6071 Impact factor: 4.016