Literature DB >> 25631907

Orbital pseudotumour as a presentation of paediatric ulcerative colitis.

Justin Hung Tiong Tan1, Hui Ping Chu, Lena Das, Thaschawee Arkachaisri.   

Abstract

A 2-year-old girl presented with a one-day history of acute-onset bilateral painful, swollen eyes and a two‑month history of loose stools. Physical examination revealed a right eyelid swelling with proptosis. Magnetic resonance imaging revealed a right orbital pseudotumour. The patient responded well to treatment with intravenous antibiotics and nonsteroidal anti-inflammatory drugs. However, three weeks later, she was readmitted with a vasculitic lesion over her left upper chest, with mucous-bloody diarrhoea. Histopathology confirmed the diagnosis of ulcerative colitis. The patient was treated with intravenous pulse methylprednisolone and sulphasalazine. Two weeks after discharge, she was readmitted for cutaneous vasculitis and worsening diarrhoea. The patient's bowel and extraintestinal diseases resolved upon addition of infliximab to her treatment regimen. Her inflammatory markers also normalised. Azathioprine was subsequently added. Infliximab was discontinued after four doses and prednisolone was tapered off. The patient remained well without any flare-up after 24 months of follow-up.

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Year:  2014        PMID: 25631907      PMCID: PMC4293973          DOI: 10.11622/smedj.2014149

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  8 in total

1.  Pseudotumor of the orbit in early childhood.

Authors:  J L Stevens; P J Rychwalski; R S Baker; R S Kielar
Journal:  J AAPOS       Date:  1998-04       Impact factor: 1.220

2.  Orbital pseudotumor and Crohn disease.

Authors:  P R Camfield; M White; H A Warner; C Lythgoe
Journal:  J Pediatr       Date:  1982-07       Impact factor: 4.406

3.  Orbital pseudotumor and Crohn disease.

Authors:  R S Young; B L Hodes; R P Cruse; K L Koch; M R Garovoy
Journal:  J Pediatr       Date:  1981-08       Impact factor: 4.406

4.  The prevalence of ocular involvement in patients with inflammatory bowel disease.

Authors:  Safiye Yilmaz; Ebru Aydemir; Ahmet Maden; Belkis Unsal
Journal:  Int J Colorectal Dis       Date:  2007-01-30       Impact factor: 2.571

5.  Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center study.

Authors:  Taxiarchis Felekis; Konstantinos Katsanos; Margarita Kitsanou; Nikolaos Trakos; Vasileios Theopistos; Dimitrios Christodoulou; Ioannis Asproudis; Epameinondas V Tsianos
Journal:  Inflamm Bowel Dis       Date:  2009-01       Impact factor: 5.325

6.  Idiopathic inflammatory orbital pseudotumor in childhood. I. Clinical characteristics.

Authors:  L S Mottow; F A Jakobiec
Journal:  Arch Ophthalmol       Date:  1978-08

7.  Asymptomatic uveitis in children with chronic inflammatory bowel diseases.

Authors:  P Hofley; J Roarty; G McGinnity; A M Griffiths; M Marcon; S Kraft; P Sherman
Journal:  J Pediatr Gastroenterol Nutr       Date:  1993-11       Impact factor: 2.839

Review 8.  Childhood orbital pseudotumor: case report and literature review.

Authors:  Dan Kitei; Francis J DiMario
Journal:  J Child Neurol       Date:  2008-01-11       Impact factor: 1.987

  8 in total

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