Han Na Lee1, Ji Young An1, Kyung Mi Lee1, Eui Jong Kim2, Woo Suk Choi1, Deog Yoon Kim3. 1. Department of Radiology, College of Medicine, Kyung Hee University, Seoul, Korea. 2. Department of Radiology, College of Medicine, Kyung Hee University, Seoul, Korea. Electronic address: euijkim@hanmail.net. 3. Department of Nuclear Medicine, College of Medicine, Kyung Hee University, Seoul, Korea.
Abstract
PURPOSE: The purpose of this study was to retrospectively evaluate symptoms, images of salivary gland dysfunction, and related clinical factors in thyroid cancer patients with total thyroidectomy followed by radioiodine therapy (RIT). METHODS: We included 164 patients who underwent thyroid ultrasonography or contrast-enhanced neck computed tomography more than 6 months later after RIT. Correlation between subjective symptoms and various RIT doses was also evaluated. RESULTS: Swelling and decreased salivary volume were the most common symptoms and images. RIT dose was the only factor with a positive correlation (P<.001). CONCLUSION: The dose of RIT should be carefully determined to minimize gland dysfunction.
PURPOSE: The purpose of this study was to retrospectively evaluate symptoms, images of salivary gland dysfunction, and related clinical factors in thyroid cancerpatients with total thyroidectomy followed by radioiodine therapy (RIT). METHODS: We included 164 patients who underwent thyroid ultrasonography or contrast-enhanced neck computed tomography more than 6 months later after RIT. Correlation between subjective symptoms and various RIT doses was also evaluated. RESULTS:Swelling and decreased salivary volume were the most common symptoms and images. RIT dose was the only factor with a positive correlation (P<.001). CONCLUSION: The dose of RIT should be carefully determined to minimize gland dysfunction.
Authors: Brynn Hollingsworth; Leigha Senter; Xiaoli Zhang; Guy N Brock; Wael Jarjour; Rebecca Nagy; Pamela Brock; Kevin R Coombes; Richard T Kloos; Matthew D Ringel; Jennifer Sipos; Ilene Lattimer; Ricardo Carrau; Sissy M Jhiang Journal: J Clin Endocrinol Metab Date: 2016-08-17 Impact factor: 5.958