Literature DB >> 25629603

Effect of speaker gaze on word learning in fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder.

David P Benjamin, Andrea S McDuffie, Angela J Thurman, Sara T Kover, Ann M Mastergeorge, Randi J Hagerman, Leonard Abbeduto.   

Abstract

PURPOSE: This study examined use of a speaker's direction of gaze during word learning by boys with fragile X syndrome (FXS), boys with nonsyndromic autism spectrum disorder (ASD), and typically developing (TD) boys.
METHOD: A fast-mapping task with follow-in and discrepant labeling conditions was administered. We expected that the use of speaker gaze would lead to participants selecting as the referent of the novel label the object to which they attended in follow-in trials and the object to which the examiner attended in the discrepant labeling trials. Participants were school-aged boys with FXS (n=18) or ASD (n=18) matched on age, intelligence quotient, and nonverbal cognition and younger TD boys (n=18) matched on nonverbal cognition.
RESULTS: All groups performed above chance in both conditions, although the TD boys performed closest to the expected pattern. Boys with FXS performed better during follow-in than in discrepant label trials, whereas TD boys and boys with ASD did equally well in both trial types. The type of trial administered first influenced subsequent responding. Error patterns also distinguished the groups.
CONCLUSION: The ability to utilize a speaker's gaze during word learning is not as well developed in boys with FXS or nonsyndromic ASD as in TD boys of the same developmental level.

Entities:  

Mesh:

Year:  2015        PMID: 25629603      PMCID: PMC4675125          DOI: 10.1044/2015_JSLHR-L-14-0136

Source DB:  PubMed          Journal:  J Speech Lang Hear Res        ISSN: 1092-4388            Impact factor:   2.297


  44 in total

Review 1.  Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.

Authors:  Gary J Bassell; Stephen T Warren
Journal:  Neuron       Date:  2008-10-23       Impact factor: 17.173

2.  Profiles of receptive and expressive language abilities in boys with comorbid fragile X syndrome and autism.

Authors:  Andrea McDuffie; Sara Kover; Leonard Abbeduto; Pamela Lewis; Ted Brown
Journal:  Am J Intellect Dev Disabil       Date:  2012-01

3.  Restricted object use in young children with autism: definition and construct validity.

Authors:  Cornelia Taylor Bruckner; Paul Yoder
Journal:  Autism       Date:  2007-03

4.  Further delineation of the executive deficit in males with fragile-X syndrome.

Authors:  John Wilding; Kim Cornish; Fehmidah Munir
Journal:  Neuropsychologia       Date:  2002       Impact factor: 3.139

5.  Between a ROC and a hard place: decision making and making decisions about using the SCQ.

Authors:  Christina Corsello; Vanessa Hus; Andrew Pickles; Susan Risi; Edwin H Cook; Bennett L Leventhal; Catherine Lord
Journal:  J Child Psychol Psychiatry       Date:  2007-09       Impact factor: 8.982

6.  Infants' contribution to the achievement of joint reference.

Authors:  D A Baldwin
Journal:  Child Dev       Date:  1991-10

Review 7.  Phenotypic variation and FMRP levels in fragile X.

Authors:  Danuta Z Loesch; Richard M Huggins; Randi J Hagerman
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2004

8.  Brain function and gaze fixation during facial-emotion processing in fragile X and autism.

Authors:  Kim M Dalton; Laura Holsen; Leonard Abbeduto; Richard J Davidson
Journal:  Autism Res       Date:  2008-08       Impact factor: 5.216

9.  Psychiatric symptoms in boys with fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder.

Authors:  Angela John Thurman; Andrea McDuffie; Randi Hagerman; Leonard Abbeduto
Journal:  Res Dev Disabil       Date:  2014-03-12

10.  A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome.

Authors:  David Hessl; Danh V Nguyen; Cherie Green; Alyssa Chavez; Flora Tassone; Randi J Hagerman; Damla Senturk; Andrea Schneider; Amy Lightbody; Allan L Reiss; Scott Hall
Journal:  J Neurodev Disord       Date:  2009-03       Impact factor: 4.025

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  5 in total

1.  Language Skills of Males with Fragile X Syndrome or Nonsyndromic Autism Spectrum Disorder.

Authors:  Angela John Thurman; Andrea McDuffie; Randi J Hagerman; Cynde K Josol; Leonard Abbeduto
Journal:  J Autism Dev Disord       Date:  2017-03

Review 2.  Updated report on tools to measure outcomes of clinical trials in fragile X syndrome.

Authors:  Dejan B Budimirovic; Elizabeth Berry-Kravis; Craig A Erickson; Scott S Hall; David Hessl; Allan L Reiss; Margaret K King; Leonard Abbeduto; Walter E Kaufmann
Journal:  J Neurodev Disord       Date:  2017-06-12       Impact factor: 4.025

3.  Verbal labels increase the salience of novel objects for preschoolers with typical development and Williams syndrome, but not in autism.

Authors:  Giacomo Vivanti; Darren R Hocking; Peter Fanning; Cheryl Dissanayake
Journal:  J Neurodev Disord       Date:  2016-12-30       Impact factor: 4.025

4.  Social communication in fragile X syndrome: pilot examination of the Brief Observation of Social Communication Change (BOSCC).

Authors:  Lucienne Ronco; Diego Cadavid; Rebecca Shaffer; Angela John Thurman; Shane Raines; So Hyun Kim
Journal:  J Neurodev Disord       Date:  2022-01-08       Impact factor: 4.025

5.  A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome.

Authors:  Andrew Ligsay; Anke Van Dijck; Danh V Nguyen; Reymundo Lozano; Yanjun Chen; Erika S Bickel; David Hessl; Andrea Schneider; Kathleen Angkustsiri; Flora Tassone; Berten Ceulemans; R Frank Kooy; Randi J Hagerman
Journal:  J Neurodev Disord       Date:  2017-08-02       Impact factor: 4.025

  5 in total

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