Literature DB >> 25629320

Correction: Association of Genetic Markers in the BCL-2 Family of Apoptosis-Related Genes with Endometrial Cancer Risk in a Chinese Population.

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Abstract

Entities:  

Year:  2015        PMID: 25629320      PMCID: PMC4309675          DOI: 10.1371/journal.pone.0117632

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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In Table 3, the minor and major alleles for several SNPs are incorrect. Please view the corrected Table 3 here.
Table 3

Association of genetic variants in BCL-2-family genes with endometrial cancer risk among 1,028 cases and 1,922 controls, the Shanghai Endometrial Cancer Genetics Study (SECGS).

Gene/chromosomeHeterozygous (Aa)Homozygous for minor allele (aa)
SNP (N = 86)Allelesa Gene regionMAFb OR (95% CI)OR (95% CI) Additive P trend c
BCL2/chr18
rs1009726C/G5UTR0.1911.08 (0.92–1.28)1.05 (0.67–1.64)0.41
rs10503077C/T5UTR0.0381.05 (0.78–1.40)3.88 (0.35–43.7)0.56
rs10503078G/A5UTR0.3780.99 (0.83–1.17)0.96 (0.75–1.22)0.80
rs11152370G/C5UTR0.1170.98 (0.81–1.19)0.66 (0.32–1.34)0.48
rs11152374G/A3UTR0.2571.09 (0.92–1.28)1.24 (0.92–1.69)0.12
rs11659758T/A5UTR0.1931.00 (0.84–1.18)0.78 (0.50–1.22)0.52
rs11872329C/T5UTR0.0371.22 (0.91–1.63)1.96 (0.45–8.59)0.13
rs11877911C/G5UTR0.0950.99 (0.80–1.22)0.94 (0.42–2.08)0.91
rs12454712T/C5UTR0.4460.95 (0.79–1.17)0.94 (0.75–1.17)0.74
rs12457190G/A5UTR0.3540.95 (0.80–1.12)1.03 (0.84–1.33)0.94
rs12457831G/C5UTR0.3590.97 (0.82–1.15)1.03 (0.79–1.32)0.97
rs12457893C/A3UTR0.3840.96 (0.81–1.13)1.07 (0.84–1.34)0.82
rs12605881A/T3UTR0.3440.93 (0.78–1.09)1.05 (0.82–1.34)0.92
rs12961672G/C5UTR0.1910.99 (0.84–1.17)0.87 (0.56–1.37)0.69
rs12961976 C/T3UTR0.1821.16 (0.97–1.38)1.30 (0.93–1.82) 0.04
rs12963776G/A5UTR0.3930.99 (0.84–1.18)1.02 (0.80–1.30)0.90
rs12967026C/G5UTR0.381.16 (0.98–1.38)1.13 (0.89–1.44)0.16
rs1381547T/C3UTR0.3841.14 (0.96–1.35)0.94 (0.75–1.19)0.99
rs1381548G/A3UTR0.2660.94 (0.80–1.11)0.75 (0.53–1.05)0.12
rs1531697T/A5UTR0.4040.98 (0.82–1.16)1.03 (0.81–1.30)0.93
rs17070739T/G5UTR0.2271.03 (0.88–1.22)1.15 (0.79–1.69)0.46
rs17070809G/A5UTR0.321.03 (0.88–1.21)0.91 (0.69–1.20)0.79
rs17070904C/T3UTR0.0880.96 (0.78–1.19)0.69 (0.27–1.79)0.54
rs17759659 A/G3UTR0.1011.27 (1.04–1.53)1.16 (0.53–2.53) 0.02
rs17841945G/A5UTR0.1250.87 (0.71–1.05)0.77 (0.40–1.47)0.11
rs1944419T/A3UTR0.4090.91 (0.77–1.08)1.01 (0.80–1.26)0.81
rs1944421T/C3UTR0.1310.96 (0.80–1.16)1.33 (0.76–2.33)0.88
rs1944423A/GPromotor0.3791.12 (0.95–1.33)1.24 (0.97–1.57)0.07
rs1982673A/C5UTR0.4350.92 (0.77–1.10)1.03 (0.82–1.29)0.98
rs2046135T/A5UTR0.1681.09 (0.92–1.29)0.94 (0.55–1.60)0.49
rs2170294 C/AIntron0.3440.95 (0.81–1.12)0.73 (0.56–0.95) 0.04
rs2199937T/C5UTR0.4891.08 (0.90–1.31)1.13 (0.91–1.41)0.28
rs2279115G/TPromotor0.3781.13 (0.95–1.34)1.19 (0.94–1.52)0.09
rs2849382A/G3UTR0.2330.93 (0.79–1.10)1.14 (0.81–1.62)0.92
rs2850755A/G3UTR0.1010.99 (0.81–1.22)0.62 (0.26–1.50)0.60
rs2850758T/C3UTR0.11.00 (0.81–1.23)0.63 (0.26–1.50)0.65
rs3744933G/T5UTR0.0760.97 (0.77–1.21)2.14 (0.91–5.05)0.61
rs3744951T/C3UTR0.0451.13 (0.87–1.48)2.42 (0.21–28.1)0.29
rs4941183A/G5UTR0.4050.90 (0.76–1.07)0.97 (0.76–1.23)0.50
rs4941185G/A5UTR0.4831.02 (0.84–1.23)1.02 (0.82–1.28)0.89
rs4941188A/G5UTR0.390.98 (0.83–1.16)0.97 (0.77–1.24)0.79
rs4941190A/G3UTR0.1031.08 (0.89–1.32)1.39 (0.62–3.13)0.30
rs4941192A/G3UTR0.0721.07 (0.86–1.34)2.20 (0.67–7.19)0.32
rs4941195 A/C3UTR0.2261.28 (1.09–1.50)1.06 (0.74–1.52) 0.03
rs4987716C/A3UTR0.0761.08 (0.87–1.35)1.07 (0.43–2.64)0.49
rs4987721T/C3UTR0.1770.88 (0.74–1.04)1.27 (0.82–1.99)0.54
rs4987739C/T3UTR0.0551.23 (0.97–1.57)1.14 (0.15–8.37)0.09
rs4987768 C/A3UTR0.2951.16 (0.98–1.37)1.32 (1.00–1.73) 0.02
rs4987808G/T5UTR0.0880.96 (0.77–1.19)0.58 (0.21–1.64)0.45
rs4987839T/C5UTR0.3970.93 (0.78–1.10)0.99 (0.78–1.25)0.70
rs6567326G/T5UTR0.4740.96 (0.80–1.15)0.87 (0.70–1.09)0.22
rs6567328A/G5UTR0.3560.91 (0.77–1.07)0.93 (0.72–1.19)0.33
rs6567334A/C3UTR0.4441.03 (0.86–1.23)1.24 (1.00–1.54)0.07
rs720321G/A5UTR0.1451.16 (0.98–1.37)N/A0.37
rs7226979T/C3UTR0.4560.94 (0.78–1.12)1.04 (0.84–1.29)0.83
rs7230177 C/T5UTR0.3230.91 (0.77–1.07)0.68 (0.51–0.90) 0.01
rs7230970T/C5UTR0.2551.02 (0.87–1.20)1.18 (0.85–1.65)0.44
rs7231901 A/C3UTR0.3270.92 (0.78–1.08)0.69 (0.52–0.91) 0.01
rs7236090T/C3UTR0.4150.92 (0.77–1.09)1.18 (0.95–1.48)0.28
rs7240319A/G5UTR0.1650.87 (0.73–1.04)0.96 (0.58–1.60)0.17
rs7240326T/C3UTR0.240.95 (0.80–1.12)0.87 (0.61–1.25)0.38
rs7243091 G/A5UTR0.1831.16 (0.98–1.37)1.82 (1.21–2.73) 0.003
rs7243985C/TPromotor0.2650.96 (0.81–1.13)1.04 (0.77–1.41)0.90
rs8083946A/G3UTR0.361.00 (0.85–1.18)0.92 (0.71–1.19)0.63
rs8084922C/G3UTR0.3380.89 (0.76–1.05)1.07 (0.83–1.38)0.86
rs8089331C/G3UTR0.240.97 (0.82–1.14)1.01 (0.72–1.40)0.81
rs8094651C/A5UTR0.4930.95 (0.79–1.14)0.87 (0.70–1.08)0.20
rs8096471G/A3UTR0.1570.90 (0.75–1.08)1.31 (0.81–2.13)0.74
rs954954A/CIntron0.1611.16 (0.97–1.37)1.15 (0.69–1.92)0.10
rs9807663 T/A3UTR0.3450.94 (0.80–1.11)0.73 (0.56–0.95) 0.04
rs9955190A/G5UTR0.2330.97 (0.83–1.15)1.11 (0.78–1.58)0.91
rs9965844G/C5UTR0.0781.00 (0.80–1.25)1.71 (0.71–4.11)0.61
BAD/chr11
rs660442G/A5UTR0.0661.13 (0.89–1.42)0.20 (0.02–1.59)0.69
rs1468558G/A5UTR0.0730.91 (0.72–1.15)0.26 (0.06–1.19)0.16
rs671976A/GIntron0.3470.86 (0.73–1.01)1.17 (0.91–1.49)0.84
rs477895T/C3UTR0.2330.91 (0.77–1.08)0.85 (0.59–1.21)0.18
BAX/chr19
rs11667229T/CPromotor0.3851.15 (0.97–1.36)0.97 (0.76–1.23)0.79
rs11667351T/GPromotor0.0671.06 (0.84–1.33)0.14 (0.02–1.12)0.77
rs1805419G/AIntron0.3751.00 (0.85–1.19)0.96 (0.74–1.23)0.93
rs8108882T/C3UTR0.470.98 (0.82–1.18)1.04 (0.84–1.30)0.73
rs905238A/G3UTR0.3550.93 (0.78–1.09)1.05 (0.81–1.34)0.88
BAK1/chr6
rs210132G/T3UTR0.3871.01 (0.85–1.19)0.90 (0.71–1.15)0.51
rs210134G/A3UTR0.261.01 (0.86–1.19)1.05 (0.77–1.43)0.78
rs210139C/AIntron0.3081.13 (0.96–1.33)1.01 (0.77–1.33)0.46
rs563751A/G3UTR0.4711.07 (0.89–1.29)0.93 (0.74–1.15)0.52
rs5745577C/TIntron0.0391.04 (0.78–1.39)1.00 (0.09–11.4)0.80
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1.  Association of genetic markers in the BCL-2 family of apoptosis-related genes with endometrial cancer risk in a Chinese population.

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