Literature DB >> 25627899

Big data mining yields novel insights on cancer.

Peng Jiang1, X Shirley Liu1.   

Abstract

Recent years have seen the rapid growth of large-scale biological data, but the effective mining and modeling of 'big data' for new biological discoveries remains a significant challenge. A new study reanalyzes expression profiles from the Gene Expression Omnibus to make novel discoveries about genes involved in DNA damage repair and genome instability in cancer.

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Year:  2015        PMID: 25627899     DOI: 10.1038/ng.3205

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  25 in total

1.  Systematic analysis of immune-related genes based on a combination of multiple databases to build a diagnostic and a prognostic risk model for hepatocellular carcinoma.

Authors:  Di-Guang Wen; Xiao-Ping Zhao; Yu You; Zuo-Jin Liu
Journal:  Cancer Immunol Immunother       Date:  2020-09-28       Impact factor: 6.968

2.  Identifying the hub gene in gastric cancer by bioinformatics analysis and in vitro experiments.

Authors:  Feiran Wang; Qiang Xue; Dong Xu; Yasu Jiang; Chong Tang; Xianchen Liu
Journal:  Cell Cycle       Date:  2020-04-15       Impact factor: 4.534

3.  Setting the Agenda for a New Discipline: Population Health Science.

Authors:  Katherine M Keyes; Sandro Galea
Journal:  Am J Public Health       Date:  2016-04       Impact factor: 9.308

Review 4.  Immune cell profiling in cancer: molecular approaches to cell-specific identification.

Authors:  Yasmin A Lyons; Sherry Y Wu; Willem W Overwijk; Keith A Baggerly; Anil K Sood
Journal:  NPJ Precis Oncol       Date:  2017-08-15

5.  Identification of Aberrantly Expressed Genes in Murine Glioblastoma During Radiotherapy via Bioinformatic Data Mining.

Authors:  Xihe Zhao; Chenxi Li; Lei Liu; Huawei Zou; Kai Li
Journal:  Onco Targets Ther       Date:  2020-05-06       Impact factor: 4.147

6.  Identification of key candidate genes and biological pathways in bladder cancer.

Authors:  Xin Gao; Yinyi Chen; Mei Chen; Shunlan Wang; Xiaohong Wen; Shufang Zhang
Journal:  PeerJ       Date:  2018-12-04       Impact factor: 2.984

7.  ISL1 promoted tumorigenesis and EMT via Aurora kinase A-induced activation of PI3K/AKT signaling pathway in neuroblastoma.

Authors:  Mengzhen Li; Chengtao Sun; Xiaoyun Bu; Feifei Sun; Yizhuo Zhang; Yi Que; Lian Zhang; Yu Zhang; Li Zhang; Suying Lu; Junting Huang; Jia Zhu; Juan Wang
Journal:  Cell Death Dis       Date:  2021-06-15       Impact factor: 8.469

8.  An efficient reversible privacy-preserving data mining technology over data streams.

Authors:  Chen-Yi Lin; Yuan-Hung Kao; Wei-Bin Lee; Rong-Chang Chen
Journal:  Springerplus       Date:  2016-08-24

9.  Development of diagnostic model of lung cancer based on multiple tumor markers and data mining.

Authors:  Zhaoxian Wang; Feifei Feng; Xiaoshan Zhou; Liju Duan; Jing Wang; Yongjun Wu; Na Wang
Journal:  Oncotarget       Date:  2017-10-19

10.  Identification of hub genes and potential molecular mechanisms in gastric cancer by integrated bioinformatics analysis.

Authors:  Ling Cao; Yan Chen; Miao Zhang; De-Quan Xu; Yan Liu; Tonglin Liu; Shi-Xin Liu; Ping Wang
Journal:  PeerJ       Date:  2018-07-02       Impact factor: 2.984

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