| Literature DB >> 25627304 |
Wahinuddin Sulaiman1, Ong Ping Seung2, Sabariah Mohd Noor3.
Abstract
Eosinophilic granulomatosis with polyangiitis is a rare primary vasculitic disease characterized by hypereosinophilia, late onset asthma and extravascular eosinophil granulomas. We report a case presented initially with acute myocardial infarction which later only proceed with asthma, skin manifestations and peripheral neuropathy. Laboratory parameters showed hypereosinohpilia with negative perinuclear pattern of antineutrophil cytoplasmic autoantibodies (p-ANCA). Skin biopsy showed leucocytoclastic vasculitis with eosinophilic infiltration while coronary angiography was normal. The patient's symptoms improved with IV methylprednisolone, pulse cyclophosphamide and azathioprine.Entities:
Keywords: Asma; Asthma; Churg Strauss syndrome; Eosinophilic granulomatosis with polyangiitis; Granulomatose eosinofílica com poliangiite; Hipereosinofilia; Hypereosinophilia; Infarto do miocárdio; Myocardial infarction; Síndrome de Churg Strauss
Mesh:
Year: 2014 PMID: 25627304 DOI: 10.1016/j.rbr.2013.03.002
Source DB: PubMed Journal: Rev Bras Reumatol ISSN: 0482-5004