Literature DB >> 25625203

Hypo- or hyper-hippo: a balancing act with bHLH transcription factors.

Tiffany A Cook1.   

Abstract

Balancing cell growth with differentiation is essential for tissue integrity. In this issue of Developmental Cell, Wang and Baker (2015) demonstrate unsuspected cross-talk between bHLH transcription factors, important regulators of organogenesis, with the Hippo tumor suppressor pathway to ensure that inappropriately differentiating cells are eliminated during development.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25625203      PMCID： PMC5534332          DOI： 10.1016/j.devcel.2015.01.007

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  9 in total

1.  A network of broadly expressed HLH genes regulates tissue-specific cell fates.

Authors:  Abhishek Bhattacharya; Nicholas E Baker
Journal:  Cell       Date:  2011-11-11       Impact factor: 41.582

Review 2.  Proneural bHLH genes in development and disease.

Authors:  Carol Huang; Jennifer A Chan; Carol Schuurmans
Journal:  Curr Top Dev Biol       Date:  2014       Impact factor: 4.897

Review 3.  Sensing the local environment: actin architecture and Hippo signalling.

Authors:  Pedro Gaspar; Nicolas Tapon
Journal:  Curr Opin Cell Biol       Date:  2014-09-25       Impact factor: 8.382

Review 4.  The ID proteins: master regulators of cancer stem cells and tumour aggressiveness.

Authors:  Anna Lasorella; Robert Benezra; Antonio Iavarone
Journal:  Nat Rev Cancer       Date:  2014-01-20       Impact factor: 60.716

5.  Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP.

Authors:  L Angus; S Moleirinho; L Herron; A Sinha; X Zhang; M Niestrata; K Dholakia; M B Prystowsky; K F Harvey; P A Reynolds; F J Gunn-Moore
Journal:  Oncogene       Date:  2011-06-13       Impact factor: 9.867

6.  Human homolog of Drosophila expanded, hEx, functions as a putative tumor suppressor in human cancer cell lines independently of the Hippo pathway.

Authors:  S Visser-Grieve; Y Hao; X Yang
Journal:  Oncogene       Date:  2011-07-25       Impact factor: 9.867

7.  Salvador-Warts-Hippo pathway in a developmental checkpoint monitoring helix-loop-helix proteins.

Authors:  Lan-Hsin Wang; Nicholas E Baker
Journal:  Dev Cell       Date:  2015-01-08       Impact factor: 12.270

8.  An evolutionary shift in the regulation of the Hippo pathway between mice and flies.

Authors:  W Bossuyt; C-L Chen; Q Chen; M Sudol; H McNeill; D Pan; A Kopp; G Halder
Journal:  Oncogene       Date:  2013-04-08       Impact factor: 9.867

Review 9.  The Hippo pathway and human cancer.

Authors:  Kieran F Harvey; Xiaomeng Zhang; David M Thomas
Journal:  Nat Rev Cancer       Date:  2013-03-07       Impact factor: 60.716
  9 in total
  1 in total

1.  Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway.

Authors:  Delphine Fagegaltier; Ilaria Falciatori; Benjamin Czech; Stephane Castel; Norbert Perrimon; Amanda Simcox; Gregory J Hannon
Journal:  Genes Dev       Date:  2016-07-15       Impact factor: 11.361
  1 in total

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