Literature DB >> 25625018

Pulmonary Tuberculosis Confirmed by Percutaneous Transthoracic Needle Biopsy: Analysis of CT Findings and Review of Correlations with Underlying Lung Disease.

Ji Young Choo1, Ki Yeol Lee1, Mi-Young Kim2, Eun-Young Kang1, Yu Whan Oh1, Seung Hwa Lee1, Bo Kyung Seo1, Bo Kyung Je1.   

Abstract

BACKGROUND: Pulmonary tuberculosis (TB) can produce unusual radiographic findings. Further, negative sputum and bronchoscopic results are common. Early diagnosis is equally as significant as treatment in the reduction of morbidity and mortality associated with pulmonary TB. AIMS: The aim of this study was to assess computed tomography (CT) findings of pulmonary TB, confirmed via percutaneous transthoracic needle biopsy (PTNB), and to correlate these findings with coexisting, underlying, lung diseases if present. STUDY
DESIGN: Cross sectional study.
METHODS: We selected eighty-four patients who were diagnosed with pulmonary TB by way of PTNB. Initially, acid-fast bacilli smear test results from these patients were negative. CT findings were reviewed to detect the presence of parenchymal abnormalities as follows: nodule(s) (<3 cm in diameter), mass (any masses ≥3 cm), daughter nodules, air-space consolidation, cavitation, calcification, lymphadenopathy, mediastinal lymphadenopathy, and associated lung parenchymal disease.
RESULTS: The CT findings of pulmonary TB confirmed by PTNB included nodules in 44 of 84 (52.4%) cases; 15 of these 44 cases (34.1%) had daughter nodules. The second most common finding was masses in 24 cases (28.6%), nine of which also had daughter nodules. 16 cases (19.0%) displayed nonsegmental consolidation. Of these 16 cases, four had coexisting usual interstitial pneumonia; four others had emphysema. Two patients with a mass had underlying pneumoconiosis.
CONCLUSION: Nodules or a mass mimicking lung cancer were the most common findings on CT scans in patients with pulmonary TB, confirmed via PTNB. The second most common finding was airspace consolidation. Therefore, PNTB is useful for the accurate diagnosis of pulmonary TB in the following cases: airspace consolidation or mass associated with underlying usual interstitial pneumonia, emphysema mimicking lung malignancy or cases of bacterial pneumonia.

Entities:  

Keywords:  Percutaneous transthoracic needle biopsy; pulmonary; tuberculosis

Year:  2014        PMID: 25625018      PMCID: PMC4299964          DOI: 10.5152/balkanmedj.2014.13187

Source DB:  PubMed          Journal:  Balkan Med J        ISSN: 2146-3123            Impact factor:   2.021


  28 in total

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Authors:  Sung-Woo Park; Jin Woo Song; Tae Sun Shim; Moo-Suk Park; Hong-Lyeol Lee; Soo-Taek Uh; Choon-Sik Park; Dong Soon Kim
Journal:  J Korean Med Sci       Date:  2012-07-25       Impact factor: 2.153

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  3 in total

Review 1.  Illustration of a number of atypical computed tomography manifestations of active pulmonary tuberculosis.

Authors:  Yi Zeng; Xiao-Li Zhai; Yì Xiáng J Wáng; Wei-Wei Gao; Chun-Mei Hu; Fei-Shen Lin; Wen-Shu Chai; Jian-Yun Wang; Yan-Ling Shi; Xin-Hua Zhou; Hui-Shan Yu; Xi-Wei Lu
Journal:  Quant Imaging Med Surg       Date:  2021-04

2.  Role of CT-guided transthoracic biopsy in the diagnosis of mycobacterial infection.

Authors:  Kyongmin Sarah Beck; Dae Hee Han; Kyo Young Lee; Seung Joon Kim
Journal:  J Investig Med       Date:  2019-01-11       Impact factor: 2.895

3.  Asymptomatic pulmonary tuberculosis mimicking lung cancer on imaging: A retrospective study.

Authors:  Shan Lang; Junping Sun; Xuning Wang; Yongjiu Xiao; Juan Wang; Mingyue Zhang; Ting Ao; Jianxin Wang
Journal:  Exp Ther Med       Date:  2017-07-09       Impact factor: 2.447

  3 in total

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