Literature DB >> 25624970

Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?

Soner Coban1, Ibrahim Keles2, İsmail Biyik3, Muhammet Guzelsoy1, Ali Rıza Turkoglu1, Nihal Ocak4.   

Abstract

INTRODUCTION: There are several studies on the relationship between increased mean platelet volume (MPV) and varicocele. We investigated the relationship between preoperative and 6-month postoperative MPV values in patients whose varicocele was corrected with surgery.
METHODS: A total of 282 patients underwent surgery at our urology clinic between December 2011 and December 2013 for primary varicocele. We retrospectively examined the records of 61 patients who came to the 6-month postoperative follow-up. The preoperative varicocele diagnosis was made with physical examination findings and supported with colour Doppler ultrasonography.
RESULTS: The varicocele was grade I in 12 patients, grade II in 34 patients and grade III in 11 patients. When the preoperative and 6-month postoperative haemoglobin (Hb), MPV, mean corpuscular volume, platelet, and platelet distribution width (PDW) values were compared, there was a significant decrease in MPV (p = 0.019), and a significant increase in Hb (p < 0.001). A noticeable increase was also present in PDW, but it was not statistically significant (p = 0.058).
CONCLUSION: We found that MPV increased in patients with varicocele and tended to decrease again after the varicocele was surgically corrected. However, we feel larger prospective series are needed.

Entities:  

Year:  2015        PMID: 25624970      PMCID: PMC4301972          DOI: 10.5489/cuaj.2113

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  27 in total

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2.  Is there any relationship between mean platelet volume and varicocele?

Authors:  S Çoban; I Keleş; I Biyik; M Güzelsoy; A R Türkoğlu; T Özgünay; N Ocak
Journal:  Andrologia       Date:  2014-01-06       Impact factor: 2.775

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Authors:  Ercan Varol; Onder Ozturk; Habil Yucel; Taner Gonca; Mehmet Has; Abdullah Dogan; Ahmet Akkaya
Journal:  Platelets       Date:  2011-05-19       Impact factor: 3.862

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Authors:  Yongsoon Park; Norberta Schoene; William Harris
Journal:  Platelets       Date:  2002 Aug-Sep       Impact factor: 3.862

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  2 in total

1.  More work needed in examining the relationship between mean platelet volume and inflammation in varicocele pathophysiology.

Authors:  Zafer Demirer; Ali Uğur Uslu
Journal:  Can Urol Assoc J       Date:  2015-09-09       Impact factor: 1.862

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Authors:  Francesco S Camoglio; Marta Peretti; Federica Bianchi; Arianna Mariotto; Nicola Zampieri
Journal:  Am J Clin Exp Urol       Date:  2015-08-08
  2 in total

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