A Murad1, P Marren1. 1. Department of Dermatology, University College Hospital Galway, Galway, Ireland.
Abstract
BACKGROUND: There has been an increase in methylchloroisothiazolinone (MCI) and especially methylisothiazolinone (MI) contact allergy in recent years. OBJECTIVES: We examined the prevalence and demography of MCI/MI and MI contact allergy in patients presenting with facial dermatitis. METHODS: Eighty patients with facial dermatitis were patch tested to the British Society for Cutaneous Allergy standard series, preservatives and own products between January 2012 and March 2014. RESULTS: A total of 14 (17.5%) patients had positive reactions to this preservative. Five (6.3%) patients tested positive to MCI/MI (0.02%), four (5%) patients tested positive to MI (0.2%) and five (6.3%) patients tested positive to both preparations. Six (7.5%) of these patients were atopic. All patients were female and the mean age was 53.8 years. Sources of allergen were in cosmetics and skin care products. CONCLUSIONS: Contact allergies to MCI/MI and MI are commoner than what was reported before and is an emerging cause of facial dermatitis. The detection rate of this allergen was increased by 5% in our cohort since the inclusion of MI (0.2%) in the standard series.
BACKGROUND: There has been an increase in methylchloroisothiazolinone (MCI) and especially methylisothiazolinone (MI) contact allergy in recent years. OBJECTIVES: We examined the prevalence and demography of MCI/MI and MI contact allergy in patients presenting with facial dermatitis. METHODS: Eighty patients with facial dermatitis were patch tested to the British Society for Cutaneous Allergy standard series, preservatives and own products between January 2012 and March 2014. RESULTS: A total of 14 (17.5%) patients had positive reactions to this preservative. Five (6.3%) patients tested positive to MCI/MI (0.02%), four (5%) patients tested positive to MI (0.2%) and five (6.3%) patients tested positive to both preparations. Six (7.5%) of these patients were atopic. All patients were female and the mean age was 53.8 years. Sources of allergen were in cosmetics and skin care products. CONCLUSIONS: Contact allergies to MCI/MI and MI are commoner than what was reported before and is an emerging cause of facial dermatitis. The detection rate of this allergen was increased by 5% in our cohort since the inclusion of MI (0.2%) in the standard series.
Authors: Jart A F Oosterhaven; Wolfgang Uter; Werner Aberer; José C Armario-Hita; Barbara K Ballmer-Weber; Andrea Bauer; Magdalena Czarnecka-Operacz; Peter Elsner; Juan García-Gavín; Ana M Giménez-Arnau; Swen M John; Beata Kręcisz; Vera Mahler; Thomas Rustemeyer; Anna Sadowska-Przytocka; Javier Sánchez-Pérez; Dagmar Simon; Skaidra Valiukevičienė; Elke Weisshaar; Marie L A Schuttelaar Journal: Contact Dermatitis Date: 2019-01-14 Impact factor: 6.600
Authors: Ana Luiza Castro Fernandes Villarinho; Maria das Graças Mota Melo; Liliane Reis Teixeira Journal: An Bras Dermatol Date: 2022-06-25 Impact factor: 2.113