Literature DB >> 25623016

Hypomethylation of MAOA's first exon region in depression: a replication study.

Philippe A Melas1, Yvonne Forsell2.   

Abstract

We recently showed that depression in females is associated with hypomethylation in the first exon region of the monoamine oxidase A (MAOA) gene. Here we report on a small-scale (n=44) replication study of MAOA methylation which (a) confirms that female subjects with a history of depression are hypomethylated compared to controls and (b) shows that females are hypermethylated in the same region compared to males.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  DNA methylation; Epigenetics; Monoamine oxidase A

Mesh：

Substances：

Year:  2015        PMID： 25623016     DOI： 10.1016/j.psychres.2015.01.003

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  12 in total

Review 1.  Epigenetic signature of MAOA and MAOB genes in mental disorders.

Authors:  Christiane Ziegler; Katharina Domschke
Journal:  J Neural Transm (Vienna)       Date:  2018-09-21       Impact factor: 3.575

Review 2.  Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons.

Authors:  Makoto Naoi; Wakako Maruyama; Masayo Shamoto-Nagai
Journal:  J Neural Transm (Vienna)       Date:  2017-12-26       Impact factor: 3.575

Review 3.  Type A monoamine oxidase and serotonin are coordinately involved in depressive disorders: from neurotransmitter imbalance to impaired neurogenesis.

Authors:  Makoto Naoi; Wakako Maruyama; Masayo Shamoto-Nagai
Journal:  J Neural Transm (Vienna)       Date:  2017-03-14       Impact factor: 3.575

4.  Monoamine Oxidase A Gene Methylation and Its Role in Posttraumatic Stress Disorder: First Evidence from the South Eastern Europe (SEE)-PTSD Study.

Authors:  Christiane Ziegler; Christiane Wolf; Miriam A Schiele; Elma Feric Bojic; Sabina Kucukalic; Emina Sabic Dzananovic; Aferdita Goci Uka; Blerina Hoxha; Valdete Haxhibeqiri; Shpend Haxhibeqiri; Nermina Kravic; Mirnesa Muminovic Umihanic; Ana Cima Franc; Nenad Jaksic; Romana Babic; Marko Pavlovic; Bodo Warrings; Alma Bravo Mehmedbasic; Dusko Rudan; Branka Aukst-Margetic; Abdulah Kucukalic; Damir Marjanovic; Dragan Babic; Nada Bozina; Miro Jakovljevic; Osman Sinanovic; Esmina Avdibegovic; Ferid Agani; Alma Dzubur-Kulenovic; Jürgen Deckert; Katharina Domschke
Journal:  Int J Neuropsychopharmacol       Date:  2018-05-01       Impact factor: 5.176

5.  Monoamine Oxidase A Hypomethylation in Obsessive-Compulsive Disorder: Reversibility By Successful Psychotherapy?

Authors:  Miriam A Schiele; Christiane Thiel; Jürgen Deckert; Michael Zaudig; Götz Berberich; Katharina Domschke
Journal:  Int J Neuropsychopharmacol       Date:  2020-05-27       Impact factor: 5.176

6.  DNA hypomethylation of the Krüppel-like factor 11 (KLF11) gene promoter: a putative biomarker of depression comorbidity in panic disorder and of non-anxious depression?

Authors:  Leonie Kollert; Miriam A Schiele; Christiane Thiel; Andreas Menke; Jürgen Deckert; Katharina Domschke
Journal:  J Neural Transm (Vienna)       Date:  2020-06-10       Impact factor: 3.575

7.  Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women.

Authors:  David Checknita; Tomas J Ekström; Erika Comasco; Kent W Nilsson; Jari Tiihonen; Sheilagh Hodgins
Journal:  J Neural Transm (Vienna)       Date:  2018-03-29       Impact factor: 3.575

8.  Experiencing community and domestic violence is associated with epigenetic changes in DNA methylation of BDNF and CLPX in adolescents.

Authors:  Fernanda Serpeloni; Daniel Nätt; Simone Gonçalves de Assis; Elizabeth Wieling; Thomas Elbert
Journal:  Psychophysiology       Date:  2019-05-06       Impact factor: 4.016

9.  Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation.

Authors:  David Checknita; Jari Tiihonen; Sheilagh Hodgins; Kent W Nilsson
Journal:  J Neural Transm (Vienna)       Date:  2021-08-23       Impact factor: 3.575

10.  The Effects of Childhood Maltreatment on Non-Suicidal Self-Injury in Male Adolescents: The Moderating Roles of the Monoamine Oxidase A (MAOA) Gene and the Catechol-O-Methyltransferase (COMT) Gene.

Authors:  Yemiao Gao; Yuke Xiong; Xia Liu; Hui Wang
Journal:  Int J Environ Res Public Health       Date:  2021-03-05       Impact factor: 3.390
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