Nívia L Nonato1, Orlando Díaz2, Oliver A Nascimento3, Jorge Dreyse2, José R Jardim3, Carmen Lisboa2. 1. Pulmonary Rehabilitation Center, Federal University of São Paulo (Unifesp), São Paulo, Brasil. Electronic address: nivia.nonato@uol.com.br. 2. Departamento de Enfermedades Respiratorias, Universidad Católica de Chile, Santiago, Chile. 3. Pulmonary Rehabilitation Center, Federal University of São Paulo (Unifesp), São Paulo, Brasil; Respiratory Division, Federal University of São Paulo (Unifesp), São Paulo, Brasil.
Abstract
INTRODUCTION: To evaluate if the association between the BODE index and deterioration in health-related quality of life is linear. To determine possible associations between the BODE index and health status evaluated by the Saint George's Respiratory Questionnaire (SGRQ) at all levels of disease severity in COPD. METHODS: A cross-sectional study was carried out on 253 patients from two Latin American respiratory centers (Brazil and Chile) with a clinical diagnosis of COPD, based on GOLD criteria. Assessment included the BODE index and the SGRQ questionnaire. RESULTS: Patients had a BODE index of 3.1±2.0; FEV1 (%) of 49±19.2; BMI (kg/m(2)) of 24.7±5.1; 6MWT distance (meters) of 444±96. Significant correlations were found between the BODE index and SGRQ total scores (r=0.5; <0.001), impact (r=0.45; <0.001) and activity (r=0.5; <0.001). From BODE score zero, HRQOL was already compromised in all SGRQ domains. SGRQ scores (total and domain) increased progressively for individual components of the BODE index, with the decrease in airflow limitation (<0.05), BMI (<0.002) and 6MWT (<0.05), and with the increase in the Modified Medical Research Council (MMRC) score (<0.05). CONCLUSION: There is an association between health-related quality of life, as assessed by the SGRQ and the BODE index within the entire spectrum of COPD severity. Even in early disease stages and BODE index zero, health-related quality of life is already impaired.
INTRODUCTION: To evaluate if the association between the BODE index and deterioration in health-related quality of life is linear. To determine possible associations between the BODE index and health status evaluated by the Saint George's Respiratory Questionnaire (SGRQ) at all levels of disease severity in COPD. METHODS: A cross-sectional study was carried out on 253 patients from two Latin American respiratory centers (Brazil and Chile) with a clinical diagnosis of COPD, based on GOLD criteria. Assessment included the BODE index and the SGRQ questionnaire. RESULTS:Patients had a BODE index of 3.1±2.0; FEV1 (%) of 49±19.2; BMI (kg/m(2)) of 24.7±5.1; 6MWT distance (meters) of 444±96. Significant correlations were found between the BODE index and SGRQ total scores (r=0.5; <0.001), impact (r=0.45; <0.001) and activity (r=0.5; <0.001). From BODE score zero, HRQOL was already compromised in all SGRQ domains. SGRQ scores (total and domain) increased progressively for individual components of the BODE index, with the decrease in airflow limitation (<0.05), BMI (<0.002) and 6MWT (<0.05), and with the increase in the Modified Medical Research Council (MMRC) score (<0.05). CONCLUSION: There is an association between health-related quality of life, as assessed by the SGRQ and the BODE index within the entire spectrum of COPD severity. Even in early disease stages and BODE index zero, health-related quality of life is already impaired.
Authors: Jose L López-Campos; Maria Abad Arranz; Carmen Calero-Acuña; Fernando Romero-Valero; Ruth Ayerbe-García; Antonio Hidalgo-Molina; Ricardo I Aguilar-Pérez-Grovas; Francisco García-Gil; Francisco Casas-Maldonado; Laura Caballero-Ballesteros; María Sánchez-Palop; Dolores Pérez-Tejero; Alejandro Segado; Jose Calvo-Bonachera; Bárbara Hernández-Sierra; Adolfo Doménech; Macarena Arroyo-Varela; Francisco González-Vargas; Juan J Cruz-Rueda Journal: PLoS One Date: 2016-03-17 Impact factor: 3.240
Authors: Kamlesh Kumar Gupta; Bidyut Roy; Shyam Chand Chaudhary; Arvind Mishra; M L Patel; Jitendra Singh; Vivek Kumar Journal: J Family Med Prim Care Date: 2018 Jan-Feb
Authors: Jose Luis López-Campos; María Abad Arranz; Carmen Calero Acuña; Fernando Romero Valero; Ruth Ayerbe García; Antonio Hidalgo Molina; Ricardo Ismael Aguilar Pérez-Grovas; Francisco García Gil; Francisco Casas Maldonado; Laura Caballero Ballesteros; María Sánchez Palop; Dolores Pérez-Tejero; Alejandro Segado; Jose Calvo Bonachera; Bárbara Hernández Sierra; Adolfo Doménech; Macarena Arroyo Varela; Francisco González Vargas; Juan Jose Cruz Rueda Journal: PLoS One Date: 2015-11-06 Impact factor: 3.240