Literature DB >> 25622946

Photocontrolled chignolin-derived β-hairpin peptidomimetics.

T Podewin1, M S Rampp, I Turkanovic, K L Karaghiosoff, W Zinth, A Hoffmann-Röder.   

Abstract

The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.

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Year:  2015        PMID: 25622946     DOI: 10.1039/c4cc10304a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Optical Control of Insulin Secretion Using an Incretin Switch.

Authors:  Johannes Broichhagen; Tom Podewin; Helena Meyer-Berg; Yorrick von Ohlen; Natalie R Johnston; Ben J Jones; Stephen R Bloom; Guy A Rutter; Anja Hoffmann-Röder; David J Hodson; Dirk Trauner
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-02       Impact factor: 15.336

2.  Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.

Authors:  Tom Podewin; Johannes Broichhagen; Christina Frost; Dieter Groneberg; Julia Ast; Helena Meyer-Berg; Nicholas H F Fine; Andreas Friebe; Martin Zacharias; David J Hodson; Dirk Trauner; Anja Hoffmann-Röder
Journal:  Chem Sci       Date:  2017-04-19       Impact factor: 9.825

  2 in total

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