| Literature DB >> 25622026 |
E J H Wee1, H Y Lau, J R Botella, M Trau.
Abstract
Developing molecular diagnostics in resource-poor settings is challenging. As such, we purpose-built a novel bridging flocculation assay for qualitative evaluation of isothermally amplified DNA by naked eye. The flocculation assay was dependent on pH, DNA polymer amounts and lengths. The method was first applied to the rapid and sensitive detection of important plant pathogens and subsequently extended to other pathogens across the animal kingdom to demonstrate the wide applications of our approach.Mesh：
Substances：
Year: 2015 PMID： 25622026 DOI： 10.1039/c4cc10068a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222