| Literature DB >> 25621816 |
Jun Ishihara1, Shino Nakadachi, Yuki Watanabe, Susumi Hatakeyama.
Abstract
An asymmetric Diels-Alder reaction of 2,4-dienols and methyl acrylate utilizing a chiral Zn(II)/Mg(II) bimetallic template with low catalyst loading was successfully achieved. The bimetallic Lewis acid template derived from (R)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol catalyzed the Diels-Alder reaction in the presence of molecular sieves 4 Å to afford various functionalized bicyclic γ-lactones with high enantiomeric purities.Entities:
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Year: 2015 PMID： 25621816 DOI： 10.1021/acs.joc.5b00055
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354