Literature DB >> 25621303

Linkage to and engagement in HIV care in western Kenya: an observational study using population-based estimates from home-based counselling and testing.

Becky L Genberg, Violet Naanyu, Juddy Wachira, Joseph W Hogan, Edwin Sang, Monicah Nyambura, Michael Odawa, Corey Duefield, Samson Ndege, Paula Braitstein.   

Abstract

BACKGROUND: Few population-based studies exist on the HIV care continuum in sub-Saharan Africa. We aimed to describe engagement in care in all adults with an existing diagnosis of HIV and to assess the time to and predictors of linkage and engagement in adults newly diagnosed via home-based counselling and testing (HBCT) in a high-prevalence setting in western Kenya.
METHODS: Data were derived from AMPATH (Academic Model Providing Access to Healthcare), which has provided HIV care in western Kenya since 2001 and the HBCT programme, which has been operating since 2007. After a widespread HBCT programme in Bunyala subcounty from December, 2009, to February, 2011, we reviewed electronic medical records to identify uptake of care in individuals (aged 13 years or older) with previously known (self-reported) infection and new (identified at HBCT) HIV diagnoses as of June 1, 2014. We defined engagement in HIV care as an initial encounter with an HIV care provider. We used Cox regression analysis to examine the predictors of engagement in care for newly diagnosed individuals.
FINDINGS: Of the 3482 adults with HIV identified at HBCT, 2122 (61%) had previously been diagnosed with HIV, of whom 1778 (84%) had had at least one clinical encounter within AMPATH. 993 (73%) of the 1360 individuals with new diagnoses at HBCT were registered in the electronic medical records, although only 209 (15%) had seen a clinician over a median of 3·4 years since diagnosis. The median time to engagement in the newly diagnosed individuals was 60 days (IQR 10–411).
INTERPRETATION: Creative and innovative strategies are needed to support people to engage with care when they are newly diagnosed with HIV through population-based case-finding initiatives. FUNDING: US President’s Emergency Plan for AIDS Relief (PEPFAR), Abbott Laboratories, the Purpleville Foundation, the Global Business Coalition, the US National Institute of Mental Health, and the Bill & Melinda Gates Foundation.

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Year:  2015        PMID: 25621303      PMCID: PMC4302338          DOI: 10.1016/S2352-3018(14)00034-4

Source DB:  PubMed          Journal:  Lancet HIV        ISSN: 2352-3018            Impact factor:   12.767


  36 in total

1.  The influence of perceptions of HIV infection, care, and identity on care entry.

Authors:  Jennifer L Fagan; Linda Beer; Pamela Garland; Eduardo Valverde; Maria Courogen; Daniel Hillman; Kathleen Brady; Jeanne Bertolli
Journal:  AIDS Care       Date:  2011-12-07

2.  Home-based HIV counselling and testing in western Kenya.

Authors:  S Kimaiyo; M C Were; C Shen; S Ndege; P Braitstein; J Sidle; J Mamlin
Journal:  East Afr Med J       Date:  2010-03

3.  What is the impact of home-based HIV counseling and testing on the clinical status of newly enrolled adults in a large HIV care program in Western Kenya?

Authors:  Juddy Wachira; Sylvester Kimaiyo; Samson Ndege; Joseph Mamlin; Paula Braitstein
Journal:  Clin Infect Dis       Date:  2011-12-08       Impact factor: 9.079

4.  Distribution of antiretroviral treatment through self-forming groups of patients in Tete Province, Mozambique.

Authors:  Tom Decroo; Barbara Telfer; Marc Biot; Jacob Maïkéré; Sergio Dezembro; Luisa Isabel Cumba; Carla das Dores; Kathryn Chu; Nathan Ford
Journal:  J Acquir Immune Defic Syndr       Date:  2011-02-01       Impact factor: 3.731

Review 5.  Risk factors, barriers and facilitators for linkage to antiretroviral therapy care: a systematic review.

Authors:  Darshini Govindasamy; Nathan Ford; Katharina Kranzer
Journal:  AIDS       Date:  2012-10-23       Impact factor: 4.177

6.  Predictors of linkage to care following community-based HIV counseling and testing in rural Kenya.

Authors:  Abigail M Hatcher; Janet M Turan; Hannah H Leslie; Lucy W Kanya; Zachary Kwena; Malory O Johnson; Starley B Shade; Elizabeth A Bukusi; Alexandre Doyen; Craig R Cohen
Journal:  AIDS Behav       Date:  2012-07

7.  Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa.

Authors:  Bruce A Larson; Kathryn Schnippel; Buyiswa Ndibongo; Thembisile Xulu; Alana Brennan; Lawrence Long; Matthew P Fox; Sydney Rosen
Journal:  J Acquir Immune Defic Syndr       Date:  2012-10-01       Impact factor: 3.731

8.  Patient enrolment into HIV care and treatment within 90 days of HIV diagnosis in eight Rwandan health facilities: a review of facility-based registers.

Authors:  Felix R Kayigamba; Mirjam I Bakker; Hadassa Fikse; Veronicah Mugisha; Anita Asiimwe; Maarten F Schim van der Loeff
Journal:  PLoS One       Date:  2012-05-11       Impact factor: 3.240

9.  Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial.

Authors:  Lara Fairall; Max O Bachmann; Carl Lombard; Venessa Timmerman; Kerry Uebel; Merrick Zwarenstein; Andrew Boulle; Daniella Georgeu; Christopher J Colvin; Simon Lewin; Gill Faris; Ruth Cornick; Beverly Draper; Mvula Tshabalala; Eduan Kotze; Cloete van Vuuren; Dewald Steyn; Ronald Chapman; Eric Bateman
Journal:  Lancet       Date:  2012-08-15       Impact factor: 79.321

Review 10.  Quantifying and addressing losses along the continuum of care for people living with HIV infection in sub-Saharan Africa: a systematic review.

Authors:  Katharina Kranzer; Darshini Govindasamy; Nathan Ford; Victoria Johnston; Stephen D Lawn
Journal:  J Int AIDS Soc       Date:  2012-11-19       Impact factor: 5.396

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  39 in total

1.  Impact of Bridging Income Generation with Group Integrated Care (BIGPIC) on Hypertension and Diabetes in Rural Western Kenya.

Authors:  Sonak D Pastakia; Simon M Manyara; Rajesh Vedanthan; Jemima H Kamano; Diana Menya; Benjamin Andama; Cleophas Chesoli; Jeremiah Laktabai
Journal:  J Gen Intern Med       Date:  2016-12-05       Impact factor: 5.128

2.  HIV-1 second-line failure and drug resistance at high-level and low-level viremia in Western Kenya.

Authors:  Rami Kantor; Allison DeLong; Leeann Schreier; Marissa Reitsma; Emanuel Kemboi; Millicent Orido; Salome Obonge; Robert Boinett; Mary Rono; Wilfred Emonyi; Katie Brooks; Mia Coetzer; Nathan Buziba; Joseph Hogan; Lameck Diero
Journal:  AIDS       Date:  2018-11-13       Impact factor: 4.177

3.  A state transition framework for patient-level modeling of engagement and retention in HIV care using longitudinal cohort data.

Authors:  Hana Lee; Joseph W Hogan; Becky L Genberg; Xiaotian K Wu; Beverly S Musick; Ann Mwangi; Paula Braitstein
Journal:  Stat Med       Date:  2017-11-22       Impact factor: 2.373

4.  Laboratory-based performance evaluation of PIMA CD4+ T-lymphocyte count point-of-care by lay-counselors in Kenya.

Authors:  Clement Zeh; Charles E Rose; Seth Inzaule; Mitesh A Desai; Fredrick Otieno; Felix Humwa; Benta Akoth; Paul Omolo; Robert T Chen; Yenew Kebede; Taraz Samandari
Journal:  J Immunol Methods       Date:  2017-05-18       Impact factor: 2.303

5.  Faith and healthcare providers' perspectives about enhancing HIV biomedical interventions in Western Kenya.

Authors:  Eunice Kamaara; Dismas Oketch; Irene Chesire; Cassandra Sutten Coats; Gladys Thomas; Yusuf Ransome; Tiara C Willie; Amy Nunn
Journal:  Glob Public Health       Date:  2019-08-07

6.  Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa.

Authors:  Mathieu Maheu-Giroux; Frank Tanser; Marie-Claude Boily; Deenan Pillay; Serene A Joseph; Till Bärnighausen
Journal:  AIDS       Date:  2017-04-24       Impact factor: 4.177

Review 7.  Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa.

Authors:  Monisha Sharma; Roger Ying; Gillian Tarr; Ruanne Barnabas
Journal:  Nature       Date:  2015-12-03       Impact factor: 49.962

8.  Experiences along the HIV care continuum: perspectives of Kenyan adolescents and caregivers.

Authors:  Winnie K Luseno; Bonita Iritani; Susannah Zietz; Suzanne Maman; Isabella I Mbai; Florence Otieno; Barrack Ongili; Denise Dion Hallfors
Journal:  Afr J AIDS Res       Date:  2017-09       Impact factor: 1.300

9.  Point of Diagnosis and Patient Retention in HIV Care in Western Kenya.

Authors:  Becky L Genberg; Hana Lee; Joseph W Hogan; Fatma Some; Juddy Wachira; Xiaotian K Wu; Paula Braitstein
Journal:  J Acquir Immune Defic Syndr       Date:  2018-08-01       Impact factor: 3.731

10.  Poor rates of linkage to HIV care and uptake of treatment after home-based HIV testing among newly diagnosed 15-to-49 year-old men and women in a high HIV prevalence setting in South Africa.

Authors:  Brendan Maughan-Brown; Sean Beckett; Ayesha B M Kharsany; Cherie Cawood; David Khanyile; Lara Lewis; Atheendar Venkataramani; Gavin George
Journal:  AIDS Care       Date:  2020-02-09
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