Literature DB >> 25621209

Current and future surgery strategies for spinal cord injuries.

Sedat Dalbayrak1, Onur Yaman1, Tevfik Yılmaz1.   

Abstract

Spinal cord trauma is a prominent cause of mortality and morbidity. In developed countries a spinal cord injury (SCI) occurs every 16 min. SCI occurs due to tissue destruction, primarily by mechanical and secondarily ischemic. Primary damage occurs at the time of the injury. It cannot be improved. Following the primary injury, secondary harm mechanisms gradually result in neuronal death. One of the prominent causes of secondary harm is energy deficit, emerging from ischemia, whose main cause in the early stage, is impaired perfusion. Due to the advanced techniques in spinal surgery, SCI is still challenging for surgeons. Spinal cord doesn't have a self-repair property. The main damage occurs at the time of the injury primarily by mechanical factors that cannot be improved. Secondarily mechanisms take part in the following sections. Spinal compression and neurological deficit are two major factors used to decide on surgery. According to advanced imaging techniques the classifications systems for spinal injury has been changed in time. Aim of the surgery is to decompress the spinal channel and to restore the spinal alinement and mobilize the patient as soon as possible. Use of neuroprotective agents as well as methods to achieve cell regeneration in addition to surgery would contribute to the solution.

Entities:  

Keywords:  Classification; Management; Mechanism; Spinal cord injury; Surgery

Year:  2015        PMID: 25621209      PMCID: PMC4303788          DOI: 10.5312/wjo.v6.i1.34

Source DB:  PubMed          Journal:  World J Orthop        ISSN: 2218-5836


  63 in total

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2.  Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats.

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Journal:  Clin Orthop Relat Res       Date:  1984-10       Impact factor: 4.176

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6.  Transpedicular screw fixation for type II Hangman's fracture: a motion preserving procedure.

Authors:  Yasser ElMiligui; Wael Koptan; Ihab Emran
Journal:  Eur Spine J       Date:  2010-04-17       Impact factor: 3.134

Review 7.  Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases.

Authors:  Andrew J Maxwell
Journal:  Nitric Oxide       Date:  2002-03       Impact factor: 4.427

8.  Anterior discectomy and fusion with internal fixation for unstable hangman's fracture.

Authors:  Hao Xu; Jie Zhao; Jiandong Yuan; Cong Wang
Journal:  Int Orthop       Date:  2008-10-14       Impact factor: 3.075

9.  The three column spine and its significance in the classification of acute thoracolumbar spinal injuries.

Authors:  F Denis
Journal:  Spine (Phila Pa 1976)       Date:  1983 Nov-Dec       Impact factor: 3.468

10.  Traumatic spondylolisthesis of the axis treated with direct C2 pars screw.

Authors:  Sedat Dalbayrak; Mesut Yilmaz; Mustafa Firidin; Sait Naderi
Journal:  Turk Neurosurg       Date:  2009-04       Impact factor: 1.003

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  6 in total

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Journal:  Neuroradiol J       Date:  2017-01-06

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Authors:  He Wang; Feng-Shou Chen; Zai-Li Zhang; Hong-Xu Zhou; Hong Ma; Xiao-Qian Li
Journal:  Mol Neurobiol       Date:  2020-10-08       Impact factor: 5.590

3.  Percutaneous pedicle screw fixation for an unstable thoracic spine fracture after a traumatic degloving injury.

Authors:  Emma Christine Celano; Griffin R Baum; Rondi B Gelbard; Faiz U Ahmad
Journal:  BMJ Case Rep       Date:  2015-12-08

4.  Neuroprotective effect of immunomodulatory peptides in rats with traumatic spinal cord injury.

Authors:  Dulce Parra-Villamar; Liliana Blancas-Espinoza; Elisa Garcia-Vences; Juan Herrera-García; Adrian Flores-Romero; Alberto Toscano-Zapien; Jonathan Vilchis Villa; Rodríguez Barrera-Roxana; Soria Zavala Karla; Antonio Ibarra; Raúl Silva-García
Journal:  Neural Regen Res       Date:  2021-07       Impact factor: 5.135

Review 5.  Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury.

Authors:  Elisa Garcia; Jorge Aguilar-Cevallos; Raul Silva-Garcia; Antonio Ibarra
Journal:  Mediators Inflamm       Date:  2016-06-23       Impact factor: 4.711

6.  Analysis of gene expression profiles in two spinal cord injury models.

Authors:  Haifeng Yuan; Bi Zhang; Junchi Ma; Yufei Zhang; Yifan Tuo; Xusheng Li
Journal:  Eur J Med Res       Date:  2022-08-23       Impact factor: 4.981

  6 in total

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