Literature DB >> 25620136

Nimbolide inhibits invasion of breast cancer.

E R Kasala1, L N Bodduluru, C C Barua.   

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Year:  2015        PMID： 25620136      PMCID： PMC6496771          DOI： 10.1111/cpr.12170

Source DB:  PubMed          Journal:  Cell Prolif        ISSN： 0960-7722            Impact factor:   6.831


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  13 in total

Review 1.  Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms.

Authors:  Lakshmi Narendra Bodduluru; Eshvendar Reddy Kasala; Nagaraju Thota; Chandana C Barua; Ramakrishna Sistla
Journal:  Toxicol In Vitro       Date:  2014-04-20       Impact factor: 3.500

2.  The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells.

Authors:  R Vidya Priyadarsini; R Senthil Murugan; P Sripriya; D Karunagaran; S Nagini
Journal:  Free Radic Res       Date:  2010-06

3.  Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21.

Authors:  Molay Kumar Roy; Masuko Kobori; Makiko Takenaka; Kazuhiko Nakahara; Hiroshi Shinmoto; Tojiro Tsushida
Journal:  Planta Med       Date:  2006-07-20       Impact factor: 3.352

4.  Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.

Authors:  P Elumalai; A Brindha Mercy; R Arunkamar; G Sharmila; F A Bhat; S Balakrishnan; P Raja Singh; J Arunakaran
Journal:  Cell Prolif       Date:  2014-12       Impact factor: 6.831

5.  Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.

Authors:  Subash C Gupta; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadav; Jayaraj Ravindran; Padmanabhan S Hema; Madan M Chaturvedi; Mangalam Nair; Bharat B Aggarwal
Journal:  J Biol Chem       Date:  2010-09-09       Impact factor: 5.157

6.  Antiproliferative effect on human cancer cell lines after treatment with nimbolide extracted from an edible part of the neem tree (Azadirachta indica).

Authors:  Molay Kumar Roy; Masuko Kobori; Makiko Takenaka; Kazuhiko Nakahara; Hiroshi Shinmoto; Seiichiro Isobe; Tojiro Tsushida
Journal:  Phytother Res       Date:  2007-03       Impact factor: 5.878

7.  The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis.

Authors:  G Harish Kumar; R Vidya Priyadarsini; G Vinothini; P Vidjaya Letchoumy; S Nagini
Journal:  Invest New Drugs       Date:  2009-05-21       Impact factor: 3.850

8.  The neem limonoids azadirachtin and nimbolide inhibit hamster cheek pouch carcinogenesis by modulating xenobiotic-metabolizing enzymes, DNA damage, antioxidants, invasion and angiogenesis.

Authors:  Ramamurthi Vidya Priyadarsini; Palrasu Manikandan; Gurram Harish Kumar; Siddavaram Nagini
Journal:  Free Radic Res       Date:  2009-05

9.  Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells.

Authors:  G Harish Kumar; K V P Chandra Mohan; A Jagannadha Rao; S Nagini
Journal:  Invest New Drugs       Date:  2008-08-22       Impact factor: 3.850

10.  Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway.

Authors:  P Elumalai; D N Gunadharini; K Senthilkumar; S Banudevi; R Arunkumar; C S Benson; G Sharmila; J Arunakaran
Journal:  Toxicol Lett       Date:  2012-10-23       Impact factor: 4.372
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  2 in total

1.  Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma.

Authors:  Neeraja M Krishnan; Hiroto Katoh; Vinayak Palve; Manisha Pareek; Reiko Sato; Shumpei Ishikawa; Binay Panda
Journal:  PeerJ       Date:  2019-03-01       Impact factor: 2.984

2.  Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model.

Authors:  Jaganathan Kowshik; Rajakishore Mishra; Josephraj Sophia; Satabdi Rautray; Kumaraswamy Anbarasu; G Deepak Reddy; Madhulika Dixit; Sundarasamy Mahalingam; Siddavaram Nagini
Journal:  Sci Rep       Date:  2017-05-17       Impact factor: 4.379
  2 in total

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