| Literature DB >> 25618346 |
Jianying Han1, Jingyu Zhang, Wenni He, Pei Huang, Ayokunmi Oyeleye, Xueting Liu, Lixin Zhang.
Abstract
Traditional Chinese medicines (TCMs) serve as a major source of a variety of drug lead compounds. In the process of natural products development, bioassay-guided isolation is a rapid and validated method for isolation of compounds with bioactivities. This chapter describes bioassay-guided separation and purification of compounds from the crude extracts of TCMs. Two approaches including size-exclusion chromatography (SEC) and high performance liquid chromatography (HPLC) are described in detail.Mesh：
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Year: 2015 PMID： 25618346 DOI： 10.1007/978-1-4939-2269-7_15
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745