| Literature DB >> 25617819 |
Neha Narula1, Tathagat Narula2, Andy Abril3.
Abstract
Adult onset Still's disease is an inflammatory disorder with a wide clinical presentation ranging from arthralgia and arthritis to rash and high-grade fever. Etiology of this rare disorder remains a mystery. We present two cases at the extreme ends of clinical presentation diagnosed with AOSD along with literature review for the same. Case one was self limiting, requiring only NSAIDS as treatment. The other was an unusual central nervous system manifestation of repeated seizures that were only responsive to pulse dose of methylprednisolone. Both met Yamaguchi criteria for adult onset Still's disease.Entities:
Keywords: Adult onset still's disease; Anakinra; Hyperferritinemia syndrome; Seizures
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Year: 2015 PMID: 25617819 DOI: 10.1016/j.autrev.2015.01.007
Source DB: PubMed Journal: Autoimmun Rev ISSN: 1568-9972 Impact factor: 9.754