Aygen Yilmaz1, Servet Ozkiraz2, Abdullah Baris Akcan2, Murat Canpolat3. 1. Division of Pediatric Gastrology, Department of Pediatrics, Akdeniz University, 07058 Antalya, Turkey. 2. Division of Neonatology, Department of Pediatrics, Antalya Research and Training Hospital, 07030 Antalya, Turkey. 3. Department of Biophysics, Biomedical Optics Research Unit, Akdeniz University, 07058 Antalya, Turkey canpolat@akdeniz.edu.tr.
Abstract
BACKGROUND: The aim of our study was to evaluate whether a portable, light-weight, light-emitting-diode phototherapy unit designed for home use is as effective as conventional blue-light fluorescent phototherapy (CFP) for treating hyperbilirubinemia in neonates. METHODS: A total of 50 patients were recruited sequentially for treatment using CFP (n = 25) and the home-type phototherapy unit (n = 25). RESULTS: The average rate of decrease in bilirubin levels was 0.17 ± 0.02 and 0.20 ± 0.01 mg/dL/hours at the end of 24 hours in the groups receiving phototherapy by CFP and home-type phototherapy units, respectively. There was no statistically significant difference in the rate of the decrease in bilirubin levels between the groups (p = 0.104). CONCLUSIONS: It has been shown that the home-type phototherapy unit is as effective as CFP units in the treatment of neonatal hyperbilirubinemia and has the potential to become a standard of care for treatment of jaundiced neonates.
BACKGROUND: The aim of our study was to evaluate whether a portable, light-weight, light-emitting-diode phototherapy unit designed for home use is as effective as conventional blue-light fluorescent phototherapy (CFP) for treating hyperbilirubinemia in neonates. METHODS: A total of 50 patients were recruited sequentially for treatment using CFP (n = 25) and the home-type phototherapy unit (n = 25). RESULTS: The average rate of decrease in bilirubin levels was 0.17 ± 0.02 and 0.20 ± 0.01 mg/dL/hours at the end of 24 hours in the groups receiving phototherapy by CFP and home-type phototherapy units, respectively. There was no statistically significant difference in the rate of the decrease in bilirubin levels between the groups (p = 0.104). CONCLUSIONS: It has been shown that the home-type phototherapy unit is as effective as CFP units in the treatment of neonatal hyperbilirubinemia and has the potential to become a standard of care for treatment of jaundiced neonates.
Authors: Berthe A M van der Geest; Johanna P de Graaf; Loes C M Bertens; Marten J Poley; Erwin Ista; René F Kornelisse; Irwin K M Reiss; Eric A P Steegers; Jasper V Been Journal: BMJ Open Date: 2019-04-20 Impact factor: 2.692