Lei Zhong1, Xing-Lu Zhou1, Juan Li2, Yan-Mei Zhang2, Yu-Fei Jiao2, Bao-Liang Guo1, Zhao-Qi Yan1, Jian-Guo Zhang3.
Abstract
OBJECTIVE: To assess the diagnostic value of the T-SPOT.TB test in cases of breast turberculosis (BTB) in China.
METHODS: We enrolled 13 female patients with primary BTB as the BTB test group and 10 healthy volunteers as the control group. The 2 groups underwent T-SPOT.TB tests and tuberculin skin tests (TSTs) before receiving a core-needle biopsy or excision biopsy. We then collected and analyzed T-SPOT.TB and TST data.
RESULTS: The sensitivity of the T-SPOT.TB test for detection of BTB (84.6%) was significantly greater than that of TST (53.8%) (P <.05); the specificity of each test (80.0% and 60.0%, respectively) for BTB was not significantly different (P >.05).
CONCLUSION: The T-SPOT.TB test could be a useful adjunct to current tests for diagnosis of BTB and could be used for early diagnosis of this condition. Copyright© by the American Society for Clinical Pathology (ASCP).
OBJECTIVE: To assess the diagnostic value of the T-SPOT.TB test in cases of breast turberculosis (BTB) in China.
METHODS: We enrolled 13 female patients with primary BTB as the BTB test group and 10 healthy volunteers as the control group. The 2 groups underwent T-SPOT.TB tests and tuberculin skin tests (TSTs) before receiving a core-needle biopsy or excision biopsy. We then collected and analyzed T-SPOT.TB and TST data.
RESULTS: The sensitivity of the T-SPOT.TB test for detection of BTB (84.6%) was significantly greater than that of TST (53.8%) (P <.05); the specificity of each test (80.0% and 60.0%, respectively) for BTB was not significantly different (P >.05).
CONCLUSION: The T-SPOT.TB test could be a useful adjunct to current tests for diagnosis of BTB and could be used for early diagnosis of this condition. Copyright© by the American Society for Clinical Pathology (ASCP).
Entities:
Keywords:
BTB; T-SPOT.TB; TST; breast tuberculosis; diagnosis; sensitivity
Mesh：
Year: 2015
PMID： 25617387 DOI： 10.1309/LMFBRT05MWV3AYIM
Source DB: PubMed Journal: Lab Med ISSN： 0007-5027